[HTML][HTML] The consequences of refractory epilepsy and its treatment
Abstract Seizures in some 30% to 40% of patients with epilepsy fail to respond to
antiepileptic drugs or other treatments. While much has been made of the risks of new drug …
antiepileptic drugs or other treatments. While much has been made of the risks of new drug …
Understanding spreading depression from headache to sudden unexpected death
O Cozzolino, M Marchese, F Trovato, E Pracucci… - Frontiers in …, 2018 - frontiersin.org
Spreading depression (SD) is a neurophysiological phenomenon characterized by abrupt
changes in intracellular ion gradients and sustained depolarization of neurons. It leads to …
changes in intracellular ion gradients and sustained depolarization of neurons. It leads to …
Postictal death is associated with tonic phase apnea in a mouse model of sudden unexpected death in epilepsy
Objective Sudden unexpected death in epilepsy (SUDEP) is an unpredictable and
devastating comorbidity of epilepsy that is believed to be due to cardiorespiratory failure …
devastating comorbidity of epilepsy that is believed to be due to cardiorespiratory failure …
Abnormalities of serotonergic neurotransmission in animal models of SUDEP
HJ Feng, CL Faingold - Epilepsy & Behavior, 2017 - Elsevier
Sudden unexpected death in epilepsy (SUDEP) is a devastating event, and both DBA/1 and
DBA/2 mice have been shown to be relevant animal models for studying SUDEP. DBA mice …
DBA/2 mice have been shown to be relevant animal models for studying SUDEP. DBA mice …
The Kv1. 1 null mouse, a model of sudden unexpected death in epilepsy (SUDEP)
BM Moore, C Jerry Jou, M Tatalovic, ES Kaufman… - …, 2014 - Wiley Online Library
Objective Kv1. 1 potassium channel null mouse (NULL) exhibits spontaneous seizure‐
related bradycardia, dies following seizure, and has been proposed as a model for vagus …
related bradycardia, dies following seizure, and has been proposed as a model for vagus …
Automated non-EEG based seizure detection: Do users have a say?
A Van de Vel, K Smets, K Wouters, B Ceulemans - Epilepsy & Behavior, 2016 - Elsevier
Purpose Quality of life of patients with epilepsy depends largely upon unpredictability of
seizure occurrence and would improve by predicting seizures or at least by detecting …
seizure occurrence and would improve by predicting seizures or at least by detecting …
[HTML][HTML] Regional cortical thickness changes accompanying generalized tonic-clonic seizures
Objective Generalized tonic-clonic seizures are accompanied by cardiovascular and
respiratory sequelae that threaten survival. The frequency of these seizures is a major risk …
respiratory sequelae that threaten survival. The frequency of these seizures is a major risk …
Genetic investigation of sudden unexpected death in epilepsy cohort by panel target resequencing
M Coll, C Allegue, S Partemi, J Mates… - International journal of …, 2016 - Springer
Sudden unexpected death in epilepsy (SUDEP) is defined as the abrupt, no traumatic,
witnessed or unwitnessed death, occurring in benign circumstances, in an individual with …
witnessed or unwitnessed death, occurring in benign circumstances, in an individual with …
[HTML][HTML] Further evidence of the association between LQT syndrome and epilepsy in a family with KCNQ1 pathogenic variant
C Tiron, O Campuzano, A Perez-Serra, I Mademont… - Seizure, 2015 - Elsevier
Purpose Ion channels are expressed both in the heart and in the brain, being advocated as
responsible for sudden unexpected death in epilepsy but few pathogenic mutations have …
responsible for sudden unexpected death in epilepsy but few pathogenic mutations have …
Targeted next-generation sequencing provides novel clues for associated epilepsy and cardiac conduction disorder/SUDEP
Sudden unexpected death in epilepsy is an unpredicted condition in patients with a
diagnosis of epilepsy, and autopsy does not conclusively identify cause of death. Although …
diagnosis of epilepsy, and autopsy does not conclusively identify cause of death. Although …