Atopic dermatitis: pathophysiology

W David Boothe, JA Tarbox, MB Tarbox - Management of atopic dermatitis …, 2017 - Springer
The pathophysiology of atopic dermatitis is complex and multifactorial, involving elements of
barrier dysfunction, alterations in cell mediated immune responses, IgE mediated …

Cellular and molecular immunologic mechanisms in patients with atopic dermatitis

T Werfel, JP Allam, T Biedermann, K Eyerich… - Journal of allergy and …, 2016 - Elsevier
Atopic dermatitis (AD) is a complex skin disease frequently associated with other diseases of
the atopic diathesis. Recent evidence supports the concept that AD can also recognize other …

Epicutaneous sensitization in the development of food allergy: what is the evidence and how can this be prevented?

HA Brough, KC Nadeau, SB Sindher, SS Alkotob… - Allergy, 2020 - Wiley Online Library
There is increasing evidence regarding the importance of allergic sensitization through the
skin. In this review, we provide an overview of the atopic march and immune mechanism …

Atopic dermatitis: the skin barrier and beyond

T Tsakok, R Woolf, CH Smith… - British Journal of …, 2019 - academic.oup.com
Background Atopic dermatitis is the most common chronic inflammatory skin disorder,
affecting up to 20% of children and 10% of adults in industrialized countries. This highly …

The exposome in atopic dermatitis

N Stefanovic, C Flohr, AD Irvine - Allergy, 2020 - Wiley Online Library
Atopic dermatitis (AD) is a complex inflammatory disorder with multiple interactions between
genetic, immune and external factors. The sum of external factors that an individual is …

The global state of psoriasis disease epidemiology: a workshop report

CEM Griffiths, JM Van der Walt, DM Ashcroft, C Flohr… - 2017 - academic.oup.com
Summary The International Psoriasis Council, a global nonprofit organization dedicated to
innovation across the full spectrum of psoriasis, led a symposium to discuss the current state …

The role of environmental exposures in atopic dermatitis

S Narla, JI Silverberg - Current allergy and asthma reports, 2020 - Springer
Abstract Purpose of Review Although genetic factors clearly play a role in the development
of atopic dermatitis (AD), the recent dramatic increase in the prevalence of AD in low-and …

Leveraging multilayered “omics” data for atopic dermatitis: a road map to precision medicine

D Ghosh, JA Bernstein, GK Khurana Hershey… - Frontiers in …, 2018 - frontiersin.org
Atopic dermatitis (AD) is a complex multifactorial inflammatory skin disease that affects~ 280
million people worldwide. About 85% of AD cases begin in childhood, a significant portion of …

The role of the environment and exposome in atopic dermatitis

N Stefanovic, AD Irvine, C Flohr - Current Treatment Options in Allergy, 2021 - Springer
Purpose of review Atopic dermatitis (AD) is a chronic inflammatory skin disorder affecting up
to 20% of children and up to 5% of adults worldwide, contributing to significant disease …

[HTML][HTML] Allergy and immunology in young children of Japan: the JECS cohort

K Yamamoto-Hanada, K Pak, M Saito-Abe… - World Allergy …, 2020 - Elsevier
Background Capturing epidemiological signatures is essential to document burdens of
disease and to design health care services, including prevention measures, clinical …