[HTML][HTML] Oral field cancerization: an update on current concepts

M Mohan, N Jagannathan - Oncology reviews, 2014 - ncbi.nlm.nih.gov
There always exists a field with genetically altered cells with a high risk of developing
premalignant and malignant lesions. It may often happen that an individual stem cell is …

[HTML][HTML] Squamous cell carcinoma–similarities and differences among anatomical sites

W Yan, II Wistuba, MR Emmert-Buck… - American journal of …, 2011 - ncbi.nlm.nih.gov
Squamous cell carcinoma (SCC) is an epithelial malignancy involving many anatomical
sites and is the most common cancer capable of metastatic spread. Development of early …

Field effect in cancer–an update

H Chai, RE Brown - Annals of Clinical & Laboratory Science, 2009 - Assoc Clin Scientists
The concept “field effect in cancer” originated in 1953 from the histopathological
observations of Slaughter and colleagues regarding the occurrence of multiple primary oral …

In vivo expression profile of the antiviral restriction factor and tumor-targeting antigen CD317/BST-2/HM1. 24/tetherin in humans

E Erikson, T Adam, S Schmidt… - Proceedings of the …, 2011 - National Acad Sciences
Human CD317 is an intrinsic immunity factor that restricts the release of enveloped viruses,
including the major pathogens HIV and Lassa virus, from infected cells in culture. Its …

MFAP2 is overexpressed in gastric cancer and promotes motility via the MFAP2/integrin α5β1/FAK/ERK pathway

L Yao, L Wu, L Zhang, W Zhou, L Wu, K He, J Ren… - Oncogenesis, 2020 - nature.com
Gastric cancer (GC) is one of the most common malignancies and its prognosis is extremely
poor. This study identifies a novel oncogene, microfibrillar-associated protein 2 (MFAP2) in …

Survivin-based treatment strategies for squamous cell carcinoma

A Santarelli, M Mascitti, L Lo Russo, D Sartini… - International journal of …, 2018 - mdpi.com
Survivin, an anti-apoptotic molecule abundantly expressed in most human neoplasms, has
been reported to contribute to cancer initiation and drug resistance in a wide variety of …

MFAP2 promotes epithelial–mesenchymal transition in gastric cancer cells by activating TGF-β/SMAD2/3 signaling pathway

JK Wang, WJ Wang, HY Cai, BB Du, P Mai… - OncoTargets and …, 2018 - Taylor & Francis
Introduction Microfibril-associated protein 2 (MFAP2) is an extracellular matrix protein that
interacts with fibrillin to modulate the function of microfibrils. MFAP2 has been reported to …

Bone marrow stromal antigen 2 expressed in cancer cells promotes mammary tumor growth and metastasis

WD Mahauad-Fernandez, KA DeMali, AK Olivier… - Breast Cancer …, 2014 - Springer
Introduction Several innate immunity genes are overexpressed in human cancers and their
roles remain controversial. Bone marrow stromal antigen 2 (BST-2) is one such gene whose …

Genes and pathways monotonically dysregulated during progression from normal through leukoplakia to gingivo-buccal oral cancer

D Das, A Maitra, CK Panda, S Ghose, B Roy… - NPJ Genomic …, 2021 - nature.com
Oral squamous cell carcinoma of the gingivo-buccal region (OSCC-GB) accounts for the
highest cancer morbidity and mortality among men in India. It has been observed that about …

MAGP1 maintains tumorigenicity and angiogenesis of laryngeal cancer by activating Wnt/β-catenin/MMP7 pathway

F Lv, X Li, Y Wang, L Hao - Carcinogenesis, 2024 - academic.oup.com
Abstract Microfibril-associated glycoprotein-1 (MAGP1), a crucial extracellular matrix protein,
contributes to the initiation and progression of different cancers. However, the role of MAGP1 …