Organic anion transporting polypeptide (OATP) family transporters accept a number of drugs
and are increasingly being recognized as important factors in governing drug and …

Angiotensin II type 1 receptor antagonists (ARBs) have become an important drug class in
the treatment of hypertension and heart failure and the protection from diabetic nephropathy …

Angiotensin II receptor blockers (ARBs) represent a new class of effective and well tolerated
orally active antihypertensive agents. Recent clinical trials have shown the added benefits of …

Ozonation, a viable option for improving wastewater effluent quality, requires process
optimization to ensure the organic micropollutants (OMPs) elimination and disinfection …

Losartan is the first orally available angiotensin-receptor antagonist without agonist
properties. Following oral administration, losartan is rapidly absorbed, reaching maximum …

Synopsis Valsartan competitively and selectively inhibits the actions of angiotensin II at the
AT 1 receptor subtype which is responsible for most of the known effects of angiotensin II. In …

Telmisartan is a potent, long‐lasting, nonpeptide antagonist of the angiotensin II type‐1
(AT1) receptor that is indicated for the treatment of essential hypertension. It selectively and …

Liver disease can modify the kinetics of drugs biotransformed by the liver. This review
updates recent developments in this field, with particular emphasis on cytochrome P450 …

The study was conducted in healthy male volunteers to evaluate the absorption, metabolic
pattern, and mode of elimination of telmisartan, a nonpeptide angiotensin II receptor …

Valsartan is a highly selective angiotensin II AT1-receptor antagonist for the treatment of
hypertension. Valsartan is mainly excreted into the bile in unchanged form. Because …