[HTML][HTML] The far-reaching scope of neuroinflammation after traumatic brain injury
DW Simon, MJ McGeachy, H Bayır, RSB Clark… - Nature Reviews …, 2017 - nature.com
The'silent epidemic'of traumatic brain injury (TBI) has been placed in the spotlight as a result
of clinical investigations and popular press coverage of athletes and veterans with single or …
of clinical investigations and popular press coverage of athletes and veterans with single or …
[HTML][HTML] Inflammation context in Alzheimer's disease, a relationship intricate to define
C Novoa, P Salazar, P Cisternas, C Gherardelli… - Biological Research, 2022 - Springer
Abstract Alzheimer's disease (AD), the most common form of dementia, is characterized by
the accumulation of amyloid β (Aβ) and hyperphosphorylated tau protein aggregates …
the accumulation of amyloid β (Aβ) and hyperphosphorylated tau protein aggregates …
[HTML][HTML] Emerging applications of nanotechnology in healthcare systems: Grand challenges and perspectives
Healthcare, as a basic human right, has often become the focus of the development of
innovative technologies. Technological progress has significantly contributed to the …
innovative technologies. Technological progress has significantly contributed to the …
[HTML][HTML] Cellular infiltration in traumatic brain injury
Traumatic brain injury leads to cellular damage which in turn results in the rapid release of
damage-associated molecular patterns (DAMPs) that prompt resident cells to release …
damage-associated molecular patterns (DAMPs) that prompt resident cells to release …
Microglial depletion with CSF1R inhibitor during chronic phase of experimental traumatic brain injury reduces neurodegeneration and neurological deficits
Chronic neuroinflammation with sustained microglial activation occurs following severe
traumatic brain injury (TBI) and is believed to contribute to subsequent neurodegeneration …
traumatic brain injury (TBI) and is believed to contribute to subsequent neurodegeneration …
Targeting microglial autophagic degradation in NLRP3 inflammasome-mediated neurodegenerative diseases
AG Wu, XG Zhou, G Qiao, LU Yu, Y Tang, LU Yan… - Ageing research …, 2021 - Elsevier
Neuroinflammation is considered as a detrimental factor in neurodegenerative diseases,
including Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD) …
including Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD) …
[HTML][HTML] NLRP3 inflammasome in neurological diseases, from functions to therapies
L Song, L Pei, S Yao, Y Wu, Y Shang - Frontiers in cellular …, 2017 - frontiersin.org
Neuroinflammation has been identified as a causative factor of multiple neurological
diseases. The nucleotide-binding oligomerization domain-, leucine-rich repeat-and pyrin …
diseases. The nucleotide-binding oligomerization domain-, leucine-rich repeat-and pyrin …
CD73 alleviates GSDMD‐mediated microglia pyroptosis in spinal cord injury through PI3K/AKT/Foxo1 signaling
S Xu, J Wang, J Zhong, M Shao, J Jiang… - Clinical and …, 2021 - Wiley Online Library
Background Neuroinflammation‐induced secondary injury is an important cause of
sustained progression of spinal cord injury. Inflammatory programmed cell death pyroptosis …
sustained progression of spinal cord injury. Inflammatory programmed cell death pyroptosis …
Obesity and neuroinflammation: a pathway to cognitive impairment
AA Miller, SJ Spencer - Brain, behavior, and immunity, 2014 - Elsevier
Obesity is a growing problem worldwide and is associated with a range of comorbidities,
including cognitive dysfunction. In this review we will address the evidence that obesity and …
including cognitive dysfunction. In this review we will address the evidence that obesity and …
[HTML][HTML] Targeting microglial activation states as a therapeutic avenue in Parkinson's disease
SR Subramaniam, HJ Federoff - Frontiers in aging neuroscience, 2017 - frontiersin.org
Parkinson's disease (PD) is a chronic and progressive disorder characterized
neuropathologically by loss of dopamine neurons in the substantia nigra, intracellular …
neuropathologically by loss of dopamine neurons in the substantia nigra, intracellular …