OBJECTIVE To systematically assess the evidence for an association between sexual
abuse and a lifetime diagnosis of psychiatric disorders. PATIENTS AND METHODS We …

Every individual experiences stressful life events. In some cases acute or chronic stress
leads to depression and other psychiatric disorders, but most people are resilient to such …

Objective: To perform a meta-analysis including all relevant studies exploring the interaction.
Data Sources: We identified studies published through November 2009 in PubMed. Study …

The hypothesis that the S allele of the 5-HTTLPR serotonin transporter promoter region is
associated with increased risk of depression, but only in individuals exposed to stressful …

Gene–environment interaction research in psychiatry is new, and is a natural ally of
neuroscience. Mental disorders have known environmental causes, but there is …

This article presents evidence suggesting that psychosocial stress may increase risk for
psychosis, especially in the case of cumulative exposure. A heuristically useful framework to …

Family studies have demonstrated genetic influences on environmental exposure: the
phenomenon of gene–environment correlation (rGE). A few molecular genetic studies have …

Current literature on the effects of chronic stress in general health converges to the concept
of allostatic load (AL). AL is the bodily 'wear and tear'that emerges with sustained allostatic …

Gene–environmental interaction (G× E) between a common functional polymorphism in the
promoter region of the serotonin transporter gene (5-HTT) and environmental adversity on …

Although antisocial personality disorder (ASPD) is more common among males and
borderline PD (BPD) is more common among females, some authors have suggested that …