Stem cells: their source, potency and use in regenerative therapies with focus on adipose-derived stem cells–a review

L Bacakova, J Zarubova, M Travnickova… - Biotechnology …, 2018 - Elsevier
Stem cells can be defined as units of biological organization that are responsible for the
development and the regeneration of organ and tissue systems. They are able to renew their …

Effect of the microenvironment on mesenchymal stem cell paracrine signaling: opportunities to engineer the therapeutic effect

GD Kusuma, J Carthew, R Lim… - Stem cells and …, 2017 - liebertpub.com
Cues from the extracellular environment, including physical stimuli, are well known to affect
mesenchymal stem cell (MSC) properties in terms of proliferation and differentiation. Many …

Prevention and treatment of radiotherapy‐induced side effects

L Barazzuol, RP Coppes, P van Luijk - Molecular oncology, 2020 - Wiley Online Library
Radiotherapy remains a mainstay of cancer treatment, being used in roughly 50% of
patients. The precision with which the radiation dose can be delivered is rapidly improving …

Bioprocessing of mesenchymal stem cells and their derivatives: Toward cell‐free therapeutics

J Phelps, A Sanati-Nezhad, M Ungrin… - Stem Cells …, 2018 - Wiley Online Library
Mesenchymal stem cells (MSCs) have attracted tremendous research interest due to their
ability to repair tissues and reduce inflammation when implanted into a damaged or …

Concise review: salivary gland regeneration: therapeutic approaches from stem cells to tissue organoids

I Lombaert, MM Movahednia, C Adine, JN Ferreira - Stem cells, 2017 - academic.oup.com
The human salivary gland (SG) has an elegant architecture of epithelial acini, connecting
ductal branching structures, vascular and neuronal networks that together function to …

Physoxia alters human mesenchymal stem cell secretome

MM Merkhan, MT Shephard… - Journal of Tissue …, 2021 - journals.sagepub.com
The human mesenchymal stem cell (hMSC) secretome has pleiotropic effects which
underpin their therapeutic potential. hMSC serum-free conditioned media (SFCM) has been …

The effects of hypoxia on the stemness properties of human dental pulp stem cells (DPSCs)

NEMB Ahmed, M Murakami, S Kaneko… - Scientific reports, 2016 - nature.com
Recent studies have demonstrated that culture under hypoxia has beneficial effects on
mesenchymal stem cells (MSCs). However, there are limitations to achieving a stable …

[HTML][HTML] Adipose-derived stromal cell in regenerative medicine: a review

RT Qomi, M Sheykhhasan - World journal of stem cells, 2017 - ncbi.nlm.nih.gov
The application of appropriate cell origin for utilizing in regenerative medicine is the major
issue. Various kinds of stem cells have been used for the tissue engineering and …

Gingival-derived mesenchymal stem cell therapy regenerated the radiated salivary glands: functional and histological evidence in murine model

HM Zayed, NH Kheir El Din, AM Abu-Seida… - Stem Cell Research & …, 2024 - Springer
Background Radiotherapy in head and neck cancer management causes degeneration of
the salivary glands (SG). This study was designed to determine the potential of gingival …

Conditioned medium of periodontal ligament mesenchymal stem cells exert anti-inflammatory effects in lipopolysaccharide-activated mouse motoneurons

TS Rajan, S Giacoppo, O Trubiani, F Diomede… - Experimental cell …, 2016 - Elsevier
Conditioned medium derived from mesenchymal stem cells (MSCs) shows
immunomodulatory and neuroprotective effects in preclinical models. Given the difficulty to …