Transforming experiences: Neurobiology of memory updating/editing

D Osorio-Gómez, MI Miranda… - Frontiers in Systems …, 2023 - frontiersin.org
Long-term memory is achieved through a consolidation process where structural and
molecular changes integrate information into a stable memory. However, environmental …

Spatial contextual recognition memory updating is modulated by dopamine release in the dorsal hippocampus from the locus coeruleus

DK Gálvez-Márquez… - Proceedings of the …, 2022 - National Acad Sciences
Detecting novelty is critical to consolidate declarative memories, such as spatial contextual
recognition memory. It has been shown that stored memories, when retrieved, are …

A locus coeruleus-dorsal CA1 dopaminergic circuit modulates memory linking

A Chowdhury, A Luchetti, G Fernandes… - Neuron, 2022 - cell.com
Individual memories are often linked so that the recall of one triggers the recall of another.
For example, contextual memories acquired close in time can be linked, and this is known to …

[HTML][HTML] Lose the fear and boost the everyday memory through memory destabilisation and reconsolidation

SH Wang - Brain Research Bulletin, 2022 - Elsevier
This review starts with a brief description of key findings from Nader et al.(2000) which
stimulate vibrant research of memory reconsolidation in the new millennium. It then zooms in …

Deficits in N-methyl-D-aspartate receptor function and synaptic plasticity in hippocampal CA1 in APP/PS1 mouse model of Alzheimer's disease

L Xu, Y Zhou, L Hu, H Jiang, Y Dong, H Shen… - Frontiers in Aging …, 2021 - frontiersin.org
The N-methyl-D-aspartate receptor is a critical molecule for synaptic plasticity and cognitive
function. Impaired synaptic plasticity is thought to contribute to the cognitive impairment …

[HTML][HTML] NMDARs control object recognition memory destabilization and reconsolidation

JI Rossato, A Radiske, MC Gonzalez, G Apolinário… - Brain Research …, 2023 - Elsevier
Object recognition memory (ORM) allows identification of previously encountered items and
is therefore crucial for remembering episodic information. In rodents, reactivation during …

Cognitive impairment in alzheimer's and metabolic diseases: a catecholaminergic hypothesis

K Guzmán-Ramos, D Osorio-Gómez… - Neuroscience, 2022 - Elsevier
Catecholaminergic transmission plays an essential role in both physiological and
pathological cognitive functions. Plastic changes subserving learning and memory …

[HTML][HTML] The Neuroscience of Active Learning and Direct Instruction

JM Dubinsky, AA Hamid - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
Throughout the educational system, students experiencing active learning pedagogy
perform better and fail less than those taught through direct instruction. Can this be ascribed …

The novel analogue of Modafinil CE-158 protects social memory against interference and triggers the release of dopamine in the nucleus accumbens of mice

K Ebner, SB Sartori, R Murau, F Kopel, P Kalaba… - Biomolecules, 2022 - mdpi.com
Previous studies have shown that atypical dopamine-transporter-inhibitors such as modafinil
and its analogues modify behavioral and cognitive functions in rodents. Here, we tested …

Perineuronal nets in the rat medial prefrontal cortex alter hippocampal-prefrontal oscillations and reshape cocaine self-administration memories

BA Sorg, JC Wingert, JD Ramos, SX Reynolds… - bioRxiv, 2024 - biorxiv.org
The medial prefrontal cortex (mPFC) is a major contributor to relapse to cocaine in humans
and to reinstatement behavior in rodent models of cocaine use disorder. Output from the …