A detailed overview of SARS-CoV-2 omicron: its sub-variants, mutations and pathophysiology, clinical characteristics, immunological landscape, immune escape, and …

S Chatterjee, M Bhattacharya, S Nag, K Dhama… - Viruses, 2023 - mdpi.com
The COVID-19 pandemic has created significant concern for everyone. Recent data from
many worldwide reports suggest that most infections are caused by the Omicron variant and …

Monkeypox: a new threat?

D Kmiec, F Kirchhoff - International journal of molecular sciences, 2022 - mdpi.com
The global vaccination programme against smallpox led to its successful eradication and
averted millions of deaths. Monkeypox virus (MPXV) is a close relative of the Variola …

[HTML][HTML] Omicron variant (B. 1.1. 529) and its sublineages: What do we know so far amid the emergence of recombinant variants of SARS-CoV-2?

M Dhawan, ARA Saied, S Mitra, FA Alhumaydhi… - Biomedicine & …, 2022 - Elsevier
Since the start of the COVID-19 pandemic, numerous variants of SARS-CoV-2 have been
reported worldwide. The advent of variants of concern (VOCs) raises severe concerns amid …

Convergent evolution in SARS-CoV-2 spike creates a variant soup from which new COVID-19 waves emerge

D Focosi, R Quiroga, S McConnell… - International journal of …, 2023 - mdpi.com
The first 2 years of the COVID-19 pandemic were mainly characterized by recurrent
mutations of SARS-CoV-2 Spike protein at residues K417, L452, E484, N501 and P681 …

SARS-CoV-2 and innate immunity: the good, the bad, and the “goldilocks”

BL Sievers, MTK Cheng, K Csiba, B Meng… - Cellular & Molecular …, 2024 - nature.com
An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of
immunity. Knowledge about this interplay can not only help us identify biological …

Determinants of Spike infectivity, processing, and neutralization in SARS-CoV-2 Omicron subvariants BA. 1 and BA. 2

C Pastorio, F Zech, S Noettger, C Jung, T Jacob… - Cell host & …, 2022 - cell.com
SARS-CoV-2 Omicron rapidly outcompeted other variants and currently dominates the
COVID-19 pandemic. Its enhanced transmission and immune evasion are thought to be …

Site specific N-and O-glycosylation mapping of the spike proteins of SARS-CoV-2 variants of concern

A Shajahan, LE Pepi, B Kumar, NB Murray, P Azadi - Scientific Reports, 2023 - nature.com
The glycosylation on the spike (S) protein of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19, modulates the viral infection …

Recent insights into SARS‐CoV‐2 omicron variant

SJR Silva, A Kohl, L Pena… - Reviews in medical …, 2023 - Wiley Online Library
The SARS‐CoV‐2 omicron variant (B. 1.1. 529) was first identified in Botswana and South
Africa, and its emergence has been associated with a steep increase in the number of SARS …

Unique mutations in SARS-CoV-2 Omicron subvariants' non-spike proteins: Potential impacts on viral pathogenesis and host immune evasion

A Hossain, S Akter, AA Rashid, S Khair… - Microbial …, 2022 - Elsevier
SARS-CoV-2 is the causative agent behind the ongoing COVID-19 pandemic. This virus is a
cumulative outcome of mutations, leading to frequent emergence of new variants and their …

The NSP4 T492I mutation increases SARS-CoV-2 infectivity by altering non-structural protein cleavage

X Lin, Z Sha, J Trimpert, D Kunec, C Jiang, Y Xiong… - Cell Host & Microbe, 2023 - cell.com
The historically dominant SARS-CoV-2 Delta variant and the currently dominant Omicron
variants carry a T492I substitution within the non-structural protein 4 (NSP4). Based on in …