Dietary polyphenols have been the focus of major interest for their potential benefits on
human health. Several preclinical studies have been conducted to provide a rationale for …

Neurological diseases are recognized as major causes of disability and mortality worldwide.
Due to the dynamic progress of diseases such as Alzheimer's disease (AD), Parkinson's …

Despite the high human interindividual variability in response to (poly) phenol consumption,
the cause-and-effect relationship between some dietary (poly) phenols (flavanols and olive …

It is well known that neurodegenerative diseases' development and progression are
accelerated due to oxidative stress and inflammation, which result in impairment of …

Biological targeting or molecular targeting is the main strategy in drug development and
disease prevention. However, the problem of “off-targets” cannot be neglected. Naturally …

Advancing age is one of the risk factors for developing many diseases, including cancer,
cardiovascular disorders, and neurodegenerative alterations, such as mild cognitive …

The gut microbiota (GM) produces different polyphenol-derived metabolites, yielding high
interindividual variability and hampering consistent health effects. GM metabotypes …

Resveratrol has long been proposed as being beneficial to human health across multiple
morbidities, yet there is currently no conclusive clinical evidence to advocate its …

Cognitive impairment and dementia are burgeoning public health concerns, especially
given the increasing longevity of the global population. These conditions not only affect the …

trans-Resveratrol can be catabolized by the gut microbiota to dihydroresveratrol, 3, 4′-
dihydroxy-trans-stilbene, lunularin, and 4-hydroxydibenzyl. These metabolites can reach …