Plant molecular farming: A viable platform for recombinant biopharmaceutical production

B Shanmugaraj, CJ I. Bulaon, W Phoolcharoen - Plants, 2020 - mdpi.com
The demand for recombinant proteins in terms of quality, quantity, and diversity is increasing
steadily, which is attracting global attention for the development of new recombinant protein …

Virus-like particles as a highly efficient vaccine platform: diversity of targets and production systems and advances in clinical development

N Kushnir, SJ Streatfield, V Yusibov - Vaccine, 2012 - Elsevier
Virus-like particles (VLPs) are a class of subunit vaccines that differentiate themselves from
soluble recombinant antigens by stronger protective immunogenicity associated with the …

Prophylactic HPV vaccination: past, present, and future

PE Castle, M Maza - Epidemiology & Infection, 2016 - cambridge.org
Human papillomavirus (HPV) is the necessary cause of cervical cancer, the fourth most
common cancer and cause of cancer-related death in females worldwide. HPV also causes …

The production of hemagglutinin‐based virus‐like particles in plants: a rapid, efficient and safe response to pandemic influenza

MA D'Aoust, MMJ Couture, N Charland… - Plant biotechnology …, 2010 - Wiley Online Library
During the last decade, the spectre of an influenza pandemic of avian origin has led to a
revision of national and global pandemic preparedness plans and has stressed the need for …

Advances in plant molecular farming

OO Obembe, JO Popoola, S Leelavathi… - Biotechnology advances, 2011 - Elsevier
Plant molecular farming (PMF) is a new branch of plant biotechnology, where plants are
engineered to produce recombinant pharmaceutical and industrial proteins in large …

Plant‐made vaccines for humans and animals

EP Rybicki - Plant biotechnology journal, 2010 - Wiley Online Library
The concept of using plants to produce high‐value pharmaceuticals such as vaccines is 20
years old this year and is only now on the brink of realisation as an established technology …

Plant molecular farming of virus‐like nanoparticles as vaccines and reagents

EP Rybicki - Wiley Interdisciplinary Reviews: Nanomedicine …, 2020 - Wiley Online Library
The use of plants for the production of virus‐like nanoparticles (VNPs) dates back to
separating natural empty capsids of plant viruses from whole virions nearly 70 years ago …

Plant-based vaccines against viruses

EP Rybicki - Virology journal, 2014 - Springer
Plant-made or “biofarmed” viral vaccines are some of the earliest products of the technology
of plant molecular farming, and remain some of the brightest prospects for the success of this …

Contributions of the international plant science community to the fight against human infectious diseases–part 1: epidemic and pandemic diseases

M Lobato Gomez, X Huang, D Alvarez… - Plant biotechnology …, 2021 - Wiley Online Library
Infectious diseases, also known as transmissible or communicable diseases, are caused by
pathogens or parasites that spread in communities by direct contact with infected individuals …

Plant-derived virus-like particles as vaccines

Q Chen, H Lai - Human vaccines & immunotherapeutics, 2013 - Taylor & Francis
Virus-like particles (VLPs) are self-assembled structures derived from viral antigens that
mimic the native architecture of viruses but lack the viral genome. VLPs have emerged as a …