Nonalcoholic fatty liver disease (NAFLD) is a disorder characterized by excess accumulation
of fat in hepatocytes (nonalcoholic fatty liver (NAFL)); in up to 40% of individuals, there are …

Hypothalamic kisspeptin neurons serve as the nodal regulatory centre of reproductive
function. These neurons are subjected to a plethora of regulatory factors that ultimately affect …

Abstract Changes in the maternal environment leading to an altered intrauterine milieu can
result in subtle insults to the fetus, promoting increased lifetime disease risk and/or disease …

Epigenetics plays an important role in orchestrating key biologic processes. Epigenetic
marks, including DNA methylation, histones, chromatin structure, and noncoding RNAs, are …

Lifestyle and genetic background are well known risk factors of cardiovascular disease
(CVD). A third contributing factor is suboptimal fetal development, due to nutrient or oxygen …

Obesity is becoming an epidemic health problem. During the last years not only genetic but
also, and primarily, environmental factors have been supposed to contribute to the …

Objective—Gestational diabetes mellitus (GDM) produces fetal hyperglycemia with
increased lifelong risks for the exposed offspring of cardiovascular and other diseases …

In recent times, there has been a significant increase in researchers' interest in the functions
of microRNAs and the role of these molecules in the pathogenesis of many multifactorial …

The molecular basis underlying fetal programming in response to maternal nutrition remains
unclear. Herein, we investigated the regulatory relationships between genes in fetal …

There is a global epidemic of chronic kidney disease (CKD) characterized by a progressive
loss of nephrons, ascribed in large part to a rising incidence of hypertension, metabolic …