[HTML][HTML] Low-intensity continuous ultrasound therapies—a systematic review of current state-of-the-art and future perspectives

SMZ Uddin, DE Komatsu, T Motyka… - Journal of clinical …, 2021 - mdpi.com
Therapeutic ultrasound has been studied for over seven decades for different medical
applications. The versatility of ultrasound applications are highly dependent on the …

[HTML][HTML] Advances in the application of low-intensity pulsed ultrasound to mesenchymal stem cells

P Xia, Y Shi, X Wang, X Li - Stem Cell Research & Therapy, 2022 - Springer
Mesenchymal stem cells (MSCs) are stem cells that exhibit self-renewal capacity and multi-
directional differentiation potential. They can be extracted from the bone marrow and …

[HTML][HTML] Targeting macrophagic SHP2 for ameliorating osteoarthritis via TLR signaling

Z Sun, Q Liu, Z Lv, J Li, X Xu, H Sun, M Wang… - … Pharmaceutica Sinica B, 2022 - Elsevier
Osteoarthritis (OA), in which M1 macrophage polarization in the synovium exacerbates
disease progression, is a major cause of cartilage degeneration and functional disabilities …

Mechanosensory and mechanotransductive processes mediated by ion channels in articular chondrocytes: Potential therapeutic targets for osteoarthritis

K Zhang, L Wang, Z Liu, B Geng, Y Teng, X Liu, Q Yi… - Channels, 2021 - Taylor & Francis
Articular cartilage consists of an extracellular matrix including many proteins as well as
embedded chondrocytes. Articular cartilage formation and function are influenced by …

[HTML][HTML] Low-intensity pulsed ultrasound delays the progression of osteoarthritis by regulating the YAP–RIPK1–NF-κB axis and influencing autophagy

C Pan, F Lu, X Hao, X Deng, J Liu, K Sun… - Journal of Translational …, 2024 - Springer
Background Osteoarthritis (OA) is a degenerative disease characterized by chronic
inflammation of the joint. As the disease progresses, patients will gradually develop …

[HTML][HTML] Photobiomodulation and low-intensity pulsed ultrasound synergistically enhance dental mesenchymal stem cells viability, migration and differentiation: an …

M Shamel, S Raafat, I El Karim, S Saber - Odontology, 2024 - Springer
Novel methods and technologies that improve mesenchymal stem cells (MSCs) proliferation
and differentiation properties are required to increase their clinical efficacy …

Effects of low-intensity pulsed ultrasound on knee osteoarthritis: A systematic review and meta-analysis of randomized controlled trials

H Chen, Z Wang, X Zhang, M Sun - Clinical Rehabilitation, 2022 - journals.sagepub.com
Objective To systemically review the effects of low-intensity pulsed ultrasound (LIPUS) on
pain relief and functional recovery in patients with knee osteoarthritis (KOA). Data sources …

Ultrasound Tissue Engineering Technology for Regulating Immune Microenvironment

X Li, X Ding, Y He, W Yi, Y Zhu, W Han… - Advanced Functional …, 2024 - Wiley Online Library
The immune microenvironment is critical for the occurrence, progression, and treatment of
diseases. Ultrasound tissue engineering technology utilizes ultrasound and the principles of …

The efficacy of low-intensity pulsed ultrasound on articular cartilage and clinical evaluations in patients with knee osteoarthritis

NG Jo, MH Ko, YH Won, SH Park… - Journal of Back and …, 2022 - content.iospress.com
BACKGROUND: While a number of preclinical studies have examined the effectiveness of
low-intensity pulsed ultrasound (LIPUS) as a potential treatment for knee osteoarthritis (OA) …

Assessment of functional roles and therapeutic potential of integrin receptors in osteoarthritis: A systematic review and meta-analysis of preclinical studies

DM Sumsuzzman, ZA Khan, J Choi, Y Hong - Ageing Research Reviews, 2022 - Elsevier
Background Integrins are heterodimeric transmembrane receptors that mediate a variety of
biological function and plays a critical role in osteoarthritis (OA) pathogenesis, which may …