Background The vast majority of medical interventions introduced into clinical development
prove unsafe or ineffective. One prominent explanation for the dismal success rate is flawed …

The 'Lambeth Conventions' is a guidance document, written in 1987 (Walker et al., 1988),
intended to be of practical value in the investigation of experimental arrhythmias induced by …

Transplantation studies in mice and rats have shown that human embryonic-stem-cell-
derived cardiomyocytes (hESC-CMs) can improve the function of infarcted hearts,,, but two …

Background: Human pluripotent stem cell (hPSC)–derived cardiomyocytes (hPSC-CMs)
have tremendous promise for application in cardiac regeneration, but their translational …

Background: The major objective of the present study was to examine the cardioprotective
effect of resveratrol, an antioxidant presents in red wines, in the rat after ischemia and …

Background Increased sympathetic activation during acute ventricular ischemia is involved
in the occurrence of life-threatening arrhythmias. Objective To test the effect of sympathetic …

Cold water submersion can induce a high incidence of cardiac arrhythmias in healthy
volunteers. Submersion and the release of breath holding can activate two powerful and …

Arrhythmia scores have been used in recent years to facilitate the analysis of arrhythmias,
particularly in relation to regional myocardial ischaemia. The recent Lambeth Conventions …

Epidemiologic investigations have shown that exercise reduces morbidity and mortality from
coronary artery disease. In this study, using a rat model, we attempted to determine whether …

Objectives: The goal of this study was to investigate the effect of pre-treatment of
mesenchymal stem cells (MSCs) with growth factors (GFs) on cardiomyogenic …