Dopamine receptors: from structure to function

C Missale, SR Nash, SW Robinson… - Physiological …, 1998 - journals.physiology.org
Missale, Cristina, S. Russel Nash, Susan W. Robinson, Mohamed Jaber, and Marc G.
Caron. Dopamine Receptors: From Structure to Function. Physiol. Rev. 78: 189–225, 1998 …

Microcircuitry of the direct and indirect pathways of the basal ganglia.

Y Smith, MD Bevan, E Shink, JP Bolam - Neuroscience, 1998 - europepmc.org
Our understanding of the organization of the basal ganglia has advanced markedly over the
last 10 years, mainly due to increased knowledge of their anatomical, neurochemical and …

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

B Giros, M Jaber, SR Jones, RM Wightman, MG Caron - Nature, 1996 - nature.com
Disruption of the mouse dopamine transporter gene results in spontaneous hyperlocomotion
despite major adaptive changes, such as decreases in neurotransmitter and receptor levels …

Striatal interneurones: chemical, physiological and morphological characterization

Y Kawaguchi, CJ Wilson, SJ Augood, PC Emson - Trends in neurosciences, 1995 - cell.com
The neostriatum is the larges* component of the basal ganglia, and the main recipient of
afferents to the basal ganglia from the cerebral cortex and thalamus. Studies of the cellular …

Dopamine receptors and brain function

M Jaber, SW Robinson, C Missale, MG Caron - Neuropharmacology, 1996 - Elsevier
In the central nervous system (CNS), dopamine is involved in the control of locomotion,
cognition, affect and neuroendocrine secretion. These actions of dopamine are mediated by …

[HTML][HTML] The striatal balancing act in drug addiction: distinct roles of direct and indirect pathway medium spiny neurons

MK Lobo, EJ Nestler - Frontiers in neuroanatomy, 2011 - frontiersin.org
The striatum plays a key role in mediating the acute and chronic effects of addictive drugs,
with drugs of abuse causing long-lasting molecular and cellular alterations in both dorsal …

Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors augments cAMP accumulation in striatal neurons: evidence for a Gs linkage to the CB1 …

M Glass, CC Felder - Journal of Neuroscience, 1997 - Soc Neuroscience
Cannabinoids act at the CB1 receptor to inhibit adenylate cyclase activity via a pertussis
toxin-sensitive G-protein. Within the striatum, CB1 receptors have been shown to be …

Molecular biology of dopamine receptors

DR Sibley, FJ Monsma Jr - Trends in pharmacological sciences, 1992 - Elsevier
The application of modem molecular biological methods has had an increasing and
dramatic impact upon the discipline of molecular neuropharmacology. This is particularly …

Localization of D1 and D2 dopamine receptors in brain with subtype-specific antibodies.

AI Levey, SM Hersch, DB Rye… - Proceedings of the …, 1993 - National Acad Sciences
Five or more dopamine receptor genes are expressed in brain. However, the
pharmacological similarities of the encoded D1-D5 receptors have hindered studies of the …

Dichotomous anatomical properties of adult striatal medium spiny neurons

TS Gertler, CS Chan, DJ Surmeier - Journal of Neuroscience, 2008 - Soc Neuroscience
Principal medium spiny projection neurons (MSNs) of the striatum have long been thought to
be homogeneous in their somatodendritic morphology and physiology. Recent work using …