Natural products as anticancer agents: current status and future perspectives

A Naeem, P Hu, M Yang, J Zhang, Y Liu, W Zhu… - Molecules, 2022 - mdpi.com
Natural products have been an invaluable and useful source of anticancer agents over the
years. Several compounds have been synthesized from natural products by modifying their …

Oscillospira-a candidate for the next-generation probiotics

J Yang, Y Li, Z Wen, W Liu, L Meng, H Huang - Gut microbes, 2021 - Taylor & Francis
Oscillospira is a class of organism that often appears in high-throughput sequencing data
but has not been purely cultured and is widely present in the animal and human intestines …

Natural products targeting the PI3K-Akt-mTOR signaling pathway in cancer: A novel therapeutic strategy

D Tewari, P Patni, A Bishayee, AN Sah… - Seminars in cancer …, 2022 - Elsevier
Abstract The phosphatidylinositol 3-kinase (PI3K)-Akt and the mammalian target of
rapamycin (mTOR) represent two vital intracellular signaling pathways, which are …

[HTML][HTML] Evaluation of synergism in drug combinations and reference models for future orientations in oncology

D Duarte, N Vale - Current Research in Pharmacology and Drug …, 2022 - Elsevier
Current cancer therapy includes a variety of strategies that can comprise only one type of
treatment or a combination of multiple treatments. Chemotherapy is still the gold standard for …

Phytochemicals in cancer cell chemosensitization: Current knowledge and future perspectives

E Khatoon, K Banik, C Harsha, BL Sailo… - Seminars in Cancer …, 2022 - Elsevier
Despite significant advancements made in the treatment of cancer during the past several
decades, it remains one of the leading causes of death worldwide killing approximately 9.6 …

Capsaicin—The major bioactive ingredient of chili peppers: Bio-efficacy and delivery systems

M Lu, C Chen, Y Lan, J Xiao, R Li, J Huang, Q Huang… - Food & function, 2020 - pubs.rsc.org
Capsaicin is the primary bioactive substance in red chili peppers, which produces the
pungent flavor. During the past few decades, pharmacological benefits of capsaicin and its …

The efficacy of natural bioactive compounds against prostate cancer: Molecular targets and synergistic activities

MAR Mia, D Dey, MR Sakib, MY Biswas… - Phytotherapy …, 2023 - Wiley Online Library
Globally, prostate cancer (PCa) is regarded as a challenging health issue, and the number
of PCa patients continues to rise despite the availability of effective treatments in recent …

Bio-based nanomaterials for cancer therapy

Y Li, X Zheng, Q Chu - Nano Today, 2021 - Elsevier
Bio-based nanomaterials have received considerable attention in cancer therapies due to
their potent characteristics such as autologous pharmaceutical, synergetic effects …

[HTML][HTML] Natural products as chemo-radiation therapy sensitizers in cancers

S Nisar, T Masoodi, KS Prabhu, S Kuttikrishnan… - Biomedicine & …, 2022 - Elsevier
Cancer is a devastating disease and is the second leading cause of death worldwide.
Surgery, chemotherapy (CT), and/or radiation therapy (RT) are the treatment of choice for …

Fucoidan and Alginate from the Brown Algae Colpomenia sinuosa and Their Combination with Vitamin C Trigger Apoptosis in Colon Cancer

R Al Monla, Z Dassouki, N Sari-Chmayssem… - Molecules, 2022 - mdpi.com
Brown seaweeds are producers of bioactive molecules which are known to inhibit
oncogenic growth. Here, we investigated the antioxidant, cytotoxic, and apoptotic effects of …