Histone modifications and non-coding RNAs: mutual epigenetic regulation and role in pathogenesis
IV Bure, MV Nemtsova, EB Kuznetsova - International Journal of …, 2022 - mdpi.com
In the last few years, more and more scientists have suggested and confirmed that
epigenetic regulators are tightly connected and form a comprehensive network of regulatory …
epigenetic regulators are tightly connected and form a comprehensive network of regulatory …
Mesenchymal stem cell‐derived exosomes for effective cartilage tissue repair and treatment of osteoarthritis
Osteoarthritis (OA) is one of the most common musculoskeletal diseases, caused by cellular
inflammatory responses and subsequent structural disruption in osteochondral extracellular …
inflammatory responses and subsequent structural disruption in osteochondral extracellular …
Exosomes derived from miR-92a-3p-overexpressing human mesenchymal stem cells enhance chondrogenesis and suppress cartilage degradation via targeting …
G Mao, Z Zhang, S Hu, Z Zhang, Z Chang… - Stem cell research & …, 2018 - Springer
Background WNT5A is known to be involved in the pathogenesis of osteoarthritis. This study
investigated the molecular mechanism of exosomal miR-92a-3p and WNT5A in …
investigated the molecular mechanism of exosomal miR-92a-3p and WNT5A in …
[HTML][HTML] Enhancement of acellular cartilage matrix scaffold by Wharton's jelly mesenchymal stem cell-derived exosomes to promote osteochondral regeneration
Articular cartilage defect repair is a problem that has long plagued clinicians. Although
mesenchymal stem cells (MSCs) have the potential to regenerate articular cartilage, they …
mesenchymal stem cells (MSCs) have the potential to regenerate articular cartilage, they …
Small extracellular vesicles from human adipose-derived stem cells attenuate cartilage degeneration
Osteoarthritis (OA) is a chronic degenerative disease of articular cartilage that is the most
common joint disease worldwide. Mesenchymal stem cells (MSCs) have been the most …
common joint disease worldwide. Mesenchymal stem cells (MSCs) have been the most …
Exosomes derived from platelet-rich plasma present a novel potential in alleviating knee osteoarthritis by promoting proliferation and inhibiting apoptosis of …
X Liu, L Wang, C Ma, G Wang, Y Zhang… - Journal of orthopaedic …, 2019 - Springer
Background Platelet-rich plasma (PRP) provides a nonsurgical approach for treating
osteoarthritis (OA). Exosomes that play vital roles in intercellular communication have been …
osteoarthritis (OA). Exosomes that play vital roles in intercellular communication have been …
Crosstalk among circRNA/lncRNA, miRNA, and mRNA in osteoarthritis
H Kong, ML Sun, XA Zhang, XQ Wang - Frontiers in Cell and …, 2021 - frontiersin.org
Osteoarthritis (OA) is a joint disease that is pervasive in life, and the incidence and mortality
of OA are increasing, causing many adverse effects on people's life. Therefore, it is very vital …
of OA are increasing, causing many adverse effects on people's life. Therefore, it is very vital …
Exosomes derived from miR-155-5p–overexpressing synovial mesenchymal stem cells prevent osteoarthritis via enhancing proliferation and migration, attenuating …
Z Wang, K Yan, G Ge, D Zhang, J Bai, X Guo… - Cell biology and …, 2021 - Springer
Synovial mesenchymal stem cells (SMSCs) have the potential to attenuate osteoarthritis
(OA)-induced injury. The role and mechanism of SMSC-derived exosomes (SMSC-Exos) …
(OA)-induced injury. The role and mechanism of SMSC-derived exosomes (SMSC-Exos) …
Exosome-transported circRNA_0001236 enhances chondrogenesis and suppress cartilage degradation via the miR-3677-3p/Sox9 axis
G Mao, Y Xu, D Long, H Sun, H Li, R Xin… - Stem Cell Research & …, 2021 - Springer
Objectives Aberrations in exosomal circular RNA (circRNA) expression have been identified
in various human diseases. In this study, we investigated whether exosomal circRNAs could …
in various human diseases. In this study, we investigated whether exosomal circRNAs could …
Mesenchymal stem cells under epigenetic control–the role of epigenetic machinery in fate decision and functional properties
A Walewska, A Janucik, M Tynecka, M Moniuszko… - Cell Death & …, 2023 - nature.com
Mesenchymal stem cells (mesenchymal stromal cells, MSC) are multipotent stem cells that
can differentiate into cells of at least three mesodermal lineages, namely adipocytes …
can differentiate into cells of at least three mesodermal lineages, namely adipocytes …