Antiviral agents for the treatment of influenza are urgently needed to circumvent the
limitations of current drugs in several critical areas: high frequencies of resistance to M2 …

The influenza virus hemagglutinin (HA) mediates the first essential step in the viral life cycle,
virus entry into target cells. Influenza virus HA is synthesised as a precursor protein in …

The broad-spectrum antiviral drug Arbidol shows efficacy against influenza viruses by
targeting the hemagglutinin (HA) fusion machinery. However, the structural basis of the …

Current flu vaccines provide only limited coverage against seasonal strains of influenza
viruses. The identification of VH1-69 antibodies that broadly neutralize almost all influenza A …

Influenza virus presents an important and persistent threat to public health worldwide, and
current vaccines provide immunity to viral isolates similar to the vaccine strain. High-affinity …

Influenza virus remains a serious health threat, owing to its ability to evade immune
surveillance through rapid genetic drift and reassortment. Here we used a human non …

Lactobacillus plantarum DK119 (DK119) isolated from the fermented Korean cabbage food
was used as a probiotic to determine its antiviral effects on influenza virus. DK119 intranasal …

Please cite this paper as: Simmerman et al.(2011) Findings from a household randomized
controlled trial of hand washing and face masks to reduce influenza transmission in …

In recent years the global market for monoclonal antibodies (mAbs) became a multi-billion-
dollar business. This success is mainly driven by treatments in the oncology and …

Seasonal epidemics caused by antigenic variations in influenza A virus remain a public
health concern and an economic burden. The isolation and characterization of broadly …