Antioxidant, antibacterial and anti-cancer activities of β-and γ-CDs/curcumin loaded in chitosan nanoparticles

N Alizadeh, S Malakzadeh - International journal of biological …, 2020 - Elsevier
Curcumin, as a naturally occurring polyphenol, has been extensively used as anticancer
and antioxidant agent due to its ability to protect cells from oxidative damage. In the present …

Interaction of drug molecules with surfactants below (Benesi-Hildebrand equation) and above the critical micelle concentration (Kawamura equation)

ZF Agatić, V Tepavčević, G Puača, M Poša - International Journal of …, 2024 - Elsevier
Drug molecules can interact with surfactant molecules either in their monomeric form, where
the Benesi-Hildebrand equation determines the binding constant, or when a micellar …

Synthesis, quantum chemical study, AIM simulation, in silico ADMET profile analysis, molecular docking and antioxidant activity assessment of aminofuran derivatives

I Azad, Y Akhter, T Khan, MI Azad, S Chandra… - Journal of Molecular …, 2020 - Elsevier
Quantum computational investigations and in silico biological evaluation of substituted
aminofuran derivatives are described in this study. The synthesized compounds were …

DFT studies on global parameters, antioxidant mechanism and molecular docking of amlodipine besylate

KPS Hussan, MS Thayyil, VK Rajan… - … Biology and Chemistry, 2019 - Elsevier
Amlodipine besylate (AMB) is a synthetic dihydropyridine calcium channel blocker with
antihypertensive and anti-anginal effects. Quantum computational investigations on AMB …

Novel findings about double-loaded curcumin-in-HPβcyclodextrin-in liposomes: effects on the lipid bilayer and drug release

AM Fernández-Romero, F Maestrelli, PA Mura… - Pharmaceutics, 2018 - mdpi.com
In this study, the encapsulation of curcumin (Cur) in “drug-in-cyclodextrin-in-liposomes
(DCL)” by following the double-loading technique (DL) was proposed, giving rise to DCL …

Design and evaluation of orally dispersible tablets containing amlodipine inclusion complexes in hydroxypropyl-β-cyclodextrin and methyl-β-cyclodextrin

M Novac, AM Musuc, EA Ozon, I Sarbu, MA Mitu… - Materials, 2022 - mdpi.com
The development of new orally dispersible tablets containing amlodipine (AML) inclusion
complexes in hydroxypropyl-β-cyclodextrin (HP-β-CD) and in methyl-β-cyclodextrin (Me-β …

A comparative study of the interactions of 5-fluorouracil and Amlodipine Besylate in aqueous β-cyclodextrin solution and drug release studies

K Kaur, R Jindal - Polymer Bulletin, 2024 - Springer
Fluorouracil is a chemotherapeutic agent used for the treatment of different kinds of cancers
and Amlodipine Besylate is a vasodilator used to cure hypertension and angina. In order to …

The Binding Mechanism Between Cyclodextrins and Anticancer Drug Noscapine: A Spectroscopic and Molecular Docking Study

A Hosseiny, Z Talebpour, Z Garkani-Nejad… - Journal of …, 2024 - Springer
In this paper the binding of noscapine (NOS) as an anticancer drug with poor bioavailability
and low solubility with beta and methyl-beta cyclodextrins (β-CD and M-β-CD) as the …

Changes in chemical stability and bioactivities of curcumin by forming inclusion complexes of beta-and Gama-cyclodextrins

N Alizadeh, S Malakzadeh - Journal of Polymer Research, 2020 - Springer
In the present study investigated the effect of curcumin (CUR), beta (β) and gamma (γ)
cyclodextrin (CD) complexes on its solubility, stability, antioxidating activity and …

Synthesis, X-ray Structure and Evaluation of Bactericidal Activity of an o-vanillin Functionalized Schiff Base

PK Mudi, S Pradhan, A Sahu, D Saha… - … Microbiology: Theory & …, 2021 - ojs.wiserpub.com
The present study reports the synthesis, crystal structure and evaluation of biological
activities of a Schiff base,[L=(Z)-2-methoxy-6-(((2-methoxyphenyl) imino) methyl) phenol]. X …