Spatial light interference microscopy: principle and applications to biomedicine
In this paper, we review spatial light interference microscopy (SLIM), a common-path, phase-
shifting interferometer, built onto a phase-contrast microscope, with white-light illumination …
shifting interferometer, built onto a phase-contrast microscope, with white-light illumination …
Quantitative phase imaging for label-free analysis of cancer cells—focus on digital holographic microscopy
Z El-Schich, A Leida Mölder, A Gjörloff Wingren - Applied Sciences, 2018 - mdpi.com
To understand complex biological processes, scientists must gain insight into the function of
individual living cells. In contrast to the imaging of fixed cells, where a single snapshot of the …
individual living cells. In contrast to the imaging of fixed cells, where a single snapshot of the …
[HTML][HTML] Large-scale tumor-associated collagen signatures identify high-risk breast cancer patients
G Xi, W Guo, D Kang, J Ma, F Fu, L Qiu, L Zheng… - Theranostics, 2021 - ncbi.nlm.nih.gov
The notion of personalized medicine demands proper prognostic biomarkers to guide the
optimal therapy for an invasive breast cancer patient. However, various risk prediction …
optimal therapy for an invasive breast cancer patient. However, various risk prediction …
Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer
K Fujita, H Kume, K Matsuzaki, A Kawashima, T Ujike… - Scientific reports, 2017 - nature.com
Extracellular vesicles (EVs) are microvesicles secreted from various cell types. We aimed to
discover a new biomarker for high Gleason score (GS) prostate cancer (PCa) in urinary EVs …
discover a new biomarker for high Gleason score (GS) prostate cancer (PCa) in urinary EVs …
[HTML][HTML] Label-free colorectal cancer screening using deep learning and spatial light interference microscopy (SLIM)
Current pathology workflow involves staining of thin tissue slices, which otherwise would be
transparent, followed by manual investigation under the microscope by a trained pathologist …
transparent, followed by manual investigation under the microscope by a trained pathologist …
Quantitative phase imaging reveals matrix stiffness-dependent growth and migration of cancer cells
Cancer progression involves complex signals within the tumor microenvironment that
orchestrate proliferation and invasive processes. The mechanical properties of the …
orchestrate proliferation and invasive processes. The mechanical properties of the …
Chronic hypoxia favours adoption to a castration-resistant cell state in prostate cancer
Predicting and treating recurrence in intermediate-risk prostate cancer patients remains a
challenge despite having identified genomic instability and hypoxia [,] as risk factors. This …
challenge despite having identified genomic instability and hypoxia [,] as risk factors. This …
Label-free quantitative evaluation of breast tissue using Spatial Light Interference Microscopy (SLIM)
Breast cancer is the most common type of cancer among women worldwide. The standard
histopathology of breast tissue, the primary means of disease diagnosis, involves manual …
histopathology of breast tissue, the primary means of disease diagnosis, involves manual …
Quantifying collagen fiber orientation in breast cancer using quantitative phase imaging
Tumor progression in breast cancer is significantly influenced by its interaction with the
surrounding stromal tissue. Specifically, the composition, orientation, and alignment of …
surrounding stromal tissue. Specifically, the composition, orientation, and alignment of …
Engineered Recombinant EGFP-Azurin Theranostic Nanosystem for Targeted Therapy of Prostate Cancer
R Bhardwaj, P Mishra - Molecular Pharmaceutics, 2023 - ACS Publications
Erythropoietin-producing hepatocellular (Eph) receptors and their ligands, ephrins, are the
largest subfamily of receptor tyrosine kinases (RTKs) that have emerged as a new class of …
largest subfamily of receptor tyrosine kinases (RTKs) that have emerged as a new class of …