Heavy metals and human health: mechanistic insight into toxicity and counter defense system of antioxidants
Heavy metals, which have widespread environmental distribution and originate from natural
and anthropogenic sources, are common environmental pollutants. In recent decades, their …
and anthropogenic sources, are common environmental pollutants. In recent decades, their …
Oxidative stress in MeHg-induced neurotoxicity
Methylmercury (MeHg) is an environmental toxicant that leads to long-lasting neurological
and developmental deficits in animals and humans. Although the molecular mechanisms …
and developmental deficits in animals and humans. Although the molecular mechanisms …
[HTML][HTML] Methylmercury's chemistry: From the environment to the mammalian brain
Methylmercury is a neurotoxicant that is found in fish and rice. MeHg's toxicity is mediated by
blockage of-SH and-SeH groups of proteins. However, the identification of MeHg's targets is …
blockage of-SH and-SeH groups of proteins. However, the identification of MeHg's targets is …
Toxicity of ethylmercury (and Thimerosal): a comparison with methylmercury
Ethylmercury (etHg) is derived from the metabolism of thimerosal (o‐carboxyphenyl‐thio‐
ethyl‐sodium salt), which is the most widely used form of organic mercury. Because of its …
ethyl‐sodium salt), which is the most widely used form of organic mercury. Because of its …
Mitochondrial redox dysfunction and environmental exposures
SW Caito, M Aschner - Antioxidants & redox signaling, 2015 - liebertpub.com
Significance: Mitochondria are structurally and biochemically diverse, even within a single
type of cell. Protein complexes localized to the inner mitochondrial membrane synthesize …
type of cell. Protein complexes localized to the inner mitochondrial membrane synthesize …
Chip-based magnetic solid-phase microextraction online coupled with microHPLC–ICPMS for the determination of mercury species in cells
H Wang, B Chen, S Zhu, X Yu, M He, B Hu - Analytical chemistry, 2016 - ACS Publications
Trace mercury speciation in cells is critical to understand its cytotoxicity and cell protection
mechanism. In this work, we fabricated a chip-based magnetic solid-phase microextraction …
mechanism. In this work, we fabricated a chip-based magnetic solid-phase microextraction …
Exposure to toxic heavy metals can influence homocysteine metabolism?
Background: Homocysteine is a sulfur amino acid whose metabolism is activated in two
pathways: remethylation to methionine, which requires folate and vitamin B12, and …
pathways: remethylation to methionine, which requires folate and vitamin B12, and …
Methylmercury-induced neurotoxicity: focus on pro-oxidative events and related consequences
Methylmercury (MeHg) is a highly neurotoxic environmental pollutant. Even though
molecular mechanisms mediating MeHg toxicity are not completely understood, several …
molecular mechanisms mediating MeHg toxicity are not completely understood, several …
Mercury risk in poultry in the Wanshan Mercury Mine, China
R Yin, W Zhang, G Sun, Z Feng, JP Hurley, L Yang… - Environmental …, 2017 - Elsevier
In this study, total mercury (THg) and methylmercury (MeHg) concentrations in muscles (leg
and breast), organs (intestine, heart, stomach, liver) and blood were investigated for …
and breast), organs (intestine, heart, stomach, liver) and blood were investigated for …
[HTML][HTML] Comparative study on methyl-and ethylmercury-induced toxicity in C6 glioma cells and the potential role of LAT-1 in mediating mercurial-thiol complexes …
LT Zimmermann, DB Santos, AA Naime, RB Leal… - Neurotoxicology, 2013 - Elsevier
Various forms of mercury possess different rates of absorption, metabolism and excretion,
and consequently, toxicity. Methylmercury (MeHg) is a highly neurotoxic organic mercurial …
and consequently, toxicity. Methylmercury (MeHg) is a highly neurotoxic organic mercurial …