Type 2 diabetes is a metabolic, chronic disorder characterized by insulin resistance and
elevated blood glucose levels. Although a large drug portfolio exists to keep the blood …

Oxidative stress (OxS) is considered a major factor in the pathophysiology of inflammatory
chronic liver diseases, including non-alcoholic liver disease (NAFLD). Chronic impairment of …

The endoplasmic reticulum (ER) is a complex and dynamic organelle that regulates many
cellular pathways, including protein synthesis, protein quality control, and lipid synthesis …

Highlights What are the main findings? For the first time, microplastics were detected and
localized by electron microscopy in human placentas. The presence of microplastics was …

The prevalence of obesity, diabetes, non-alcoholic fatty liver disease, and related metabolic
disorders has been steadily increasing in the past few decades. Apart from the …

The endoplasmic reticulum (ER) is not only responsible for protein synthesis and folding but
also plays a critical role in sensing cellular stress and maintaining cellular homeostasis …

Psoriasis is an immune-mediated systemic disease with associated comorbidities, including
metabolic syndrome (MetS) which contributes substantially to premature mortality in patients …

Cancer is one of the leading causes of death around the world and although the different
clinical approaches have helped to increase survival rates, incidence is still high and so its …

Aging accompanied by several age-related complications, is a multifaceted inevitable
biological progression involving various genetic, environmental, and lifestyle factors. The …

N6-methyladenosine (m6A) is the most prevalent internal mRNA modification. m6A can be
installed by the methyltransferase complex and removed by demethylases, which are …