When investigating Mendelian disease using exome or genome sequencing, distinguishing
disease-causing genetic variants from the multitude of candidate variants is a complex …

The falling cost of genome sequencing is having a marked impact on the research
community with respect to which genomes are sequenced and how and where they are …

Conifers dominate the world's forest ecosystems and are the most widely planted tree
species. Their giant and complex genomes present great challenges for assembling a …

We report de novo genome assemblies, transcriptomes, annotations, and methylomes for
the 26 inbreds that serve as the founders for the maize nested association mapping …

The flowering plant Arabidopsis thaliana is a dicot model organism for research in many
aspects of plant biology. A comprehensive annotation of its genome paves the way for …

Chenopodium quinoa (quinoa) is a highly nutritious grain identified as an important crop to
improve world food security. Unfortunately, few resources are available to facilitate its …

This unit describes how to use the genome annotation and curation tools MAKER and
MAKER‐P to annotate protein‐coding and noncoding RNA genes in newly assembled …

Background Second-generation sequencing technologies are precipitating major shifts with
regards to what kinds of genomes are being sequenced and how they are annotated. While …

Simple Summary Due to the development of high-throughput sequencing technologies,
computational genome annotation of sequences has become one of the principal research …

Plant terrestrialization brought forth the land plants (embryophytes). Embryophytes account
for most of the biomass on land and evolved from streptophyte algae in a singular event …