5-Fluorouracil nano-delivery systems as a cutting-edge for cancer therapy

AA Valencia-Lazcano, D Hassan, M Pourmadadi… - European Journal of …, 2023 - Elsevier
Fluorouracil (5-FU) is amongst the most commonly used antimetabolite chemotherapeutic
agents in recent decades. However, its low bioavailability, short half-life, rapid metabolism …

[HTML][HTML] Nano-based drug delivery systems: Conventional drug delivery routes, recent developments and future prospects

A Sultana, M Zare, V Thomas, TSS Kumar… - Medicine in Drug …, 2022 - Elsevier
Drug delivery can be defined as the group of approaches a drug or pharmacologically active
agent can be transported to the target cell to treat disease or health issue. Conventional …

Clinical translation of advanced colonic drug delivery technologies

A Awad, CM Madla, LE McCoubrey, F Ferraro… - Advanced drug delivery …, 2022 - Elsevier
Targeted drug delivery to the colon offers a myriad of benefits, including treatment of local
diseases, direct access to unique therapeutic targets and the potential for increasing …

Targeted delivery of drugs and genes using polymer nanocarriers for cancer therapy

W Xia, Z Tao, B Zhu, W Zhang, C Liu, S Chen… - International journal of …, 2021 - mdpi.com
Cancer is one of the primary causes of worldwide human deaths. Most cancer patients
receive chemotherapy and radiotherapy, but these treatments are usually only partially …

[HTML][HTML] A comprehensive review of nanoparticles: from classification to application and toxicity

F Eker, H Duman, E Akdaşçi, E Bolat, S Sarıtaş… - Molecules, 2024 - mdpi.com
Nanoparticles are structures that possess unique properties with high surface area-to-
volume ratio. Their small size, up to 100 nm, and potential for surface modifications have …

[HTML][HTML] Identification of ferroptosis as a novel mechanism for antitumor activity of natural product derivative a2 in gastric cancer

Y Liu, Z Song, Y Liu, X Ma, W Wang, Y Ke, Y Xu… - … Pharmaceutica Sinica B, 2021 - Elsevier
Ferroptosis is a type of cell death accompanied by iron-dependent lipid peroxidation, thus
stimulating ferroptosis may be a potential strategy for treating gastric cancer, therapeutic …

A Mini-Review on Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Topical Delivery of Phytochemicals for the Treatment of Acne Vulgaris

R Chutoprapat, P Kopongpanich, LW Chan - Molecules, 2022 - mdpi.com
Acne vulgaris (acne) is one of the most common dermatological problems affecting
adolescents and young adults. Although acne may not lead to serious medical …

Investigating the therapeutic promise of drug-repurposed-loaded nanocarriers: A pioneering strategy in advancing colorectal cancer treatment

AT Mneimneh, N Darwiche, MM Mehanna - International Journal of …, 2024 - Elsevier
Globally, colorectal cancer is a major health problem that ranks in third place in terms of
occurrences and second in terms of mortality worldwide. New cases increase annually, with …

[HTML][HTML] Advances in the delivery of anticancer drugs by nanoparticles and chitosan-based nanoparticles

J Prieložná, V Mikušová, P Mikuš - International Journal of Pharmaceutics …, 2024 - Elsevier
Cancer is the leading cause of death globally, and conventional treatments have limited
efficacy with severe side effects. The use of nanotechnology has the potential to reduce the …

Application of Wharton jelly-derived mesenchymal stem cells in patients with pulmonary fibrosis

M Saleh, SZ Fotook Kiaei, M Kavianpour - Stem Cell Research & Therapy, 2022 - Springer
Pulmonary fibrosis is a devastating disease that eventually leads to death and respiratory
failure. Despite the wide range of drugs, including corticosteroids, endothelin antagonist …