Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis
Nanotechnology could improve our understanding of the pathophysiology of atherosclerosis
and contribute to the development of novel diagnostic and therapeutic strategies to further …
and contribute to the development of novel diagnostic and therapeutic strategies to further …
[HTML][HTML] The role of vascular biomarkers for primary and secondary prevention. A position paper from the European Society of Cardiology Working Group on …
C Vlachopoulos, P Xaplanteris, V Aboyans… - Atherosclerosis, 2015 - Elsevier
While risk scores are invaluable tools for adapted preventive strategies, a significant gap
exists between predicted and actual event rates. Additional tools to further stratify the risk of …
exists between predicted and actual event rates. Additional tools to further stratify the risk of …
The assessment of endothelial function: from research into clinical practice
AJ Flammer, T Anderson, DS Celermajer, MA Creager… - Circulation, 2012 - Am Heart Assoc
The discovery of nitric oxide (NO) as a crucial endothe-lium-derived molecule for vascular
relaxation and the recognition of the endothelium as more than a passive interface between …
relaxation and the recognition of the endothelium as more than a passive interface between …
Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials …
Objective To investigate the effects on cardiovascular outcomes of drug interventions that
increase high density lipoprotein levels. Design Meta-analysis. Studies reviewed …
increase high density lipoprotein levels. Design Meta-analysis. Studies reviewed …
Calcific aortic stenosis: a disease of the valve and the myocardium
MR Dweck, NA Boon, DE Newby - Journal of the American College of …, 2012 - jacc.org
Although aortic stenosis is a common condition associated with major morbidity, mortality,
and health economic costs, there are currently no medical interventions capable of delaying …
and health economic costs, there are currently no medical interventions capable of delaying …
Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport
High-density lipoprotein (HDL) has been proposed to have several antiatherosclerotic
properties, including the ability to mediate macrophage cholesterol efflux, antioxidant …
properties, including the ability to mediate macrophage cholesterol efflux, antioxidant …
Imaging atherosclerosis
Advances in atherosclerosis imaging technology and research have provided a range of
diagnostic tools to characterize high-risk plaque in vivo; however, these important vascular …
diagnostic tools to characterize high-risk plaque in vivo; however, these important vascular …
Intensification of statin therapy results in a rapid reduction in atherosclerotic inflammation: results of a multicenter fluorodeoxyglucose-positron emission tomography …
Objectives: The study sought to test whether high-dose statin treatment would result in
greater reductions in plaque inflammation than low-dose statins, using fluorodeoxyglucose …
greater reductions in plaque inflammation than low-dose statins, using fluorodeoxyglucose …
Clinical quantitative coronary artery stenosis and coronary atherosclerosis imaging: a Consensus Statement from the Quantitative Cardiovascular Imaging Study …
AJV Mézquita, F Biavati, V Falk, H Alkadhi… - Nature Reviews …, 2023 - nature.com
The detection and characterization of coronary artery stenosis and atherosclerosis using
imaging tools are key for clinical decision-making in patients with known or suspected …
imaging tools are key for clinical decision-making in patients with known or suspected …
PET imaging of inflammation in atherosclerosis
PET imaging of atherosclerosis can quantify several in vivo pathological processes
occurring within the arterial system. 18F-fluorodeoxyglucose (FDG) is the most-commonly …
occurring within the arterial system. 18F-fluorodeoxyglucose (FDG) is the most-commonly …