Isolation and characterization of extracellular vesicle subpopulations from tissues
R Crescitelli, C Lässer, J Lötvall - Nature protocols, 2021 - nature.com
Extracellular vesicles (EVs) are lipid bilayered membrane structures released by all cells.
Most EV studies have been performed by using cell lines or body fluids, but the number of …
Most EV studies have been performed by using cell lines or body fluids, but the number of …
Focus on the glycerophosphocholine pathway in choline phospholipid metabolism of cancer
Activated choline metabolism is a hallmark of carcinogenesis and tumor progression, which
leads to elevated levels of phosphocholine and glycerophosphocholine in all types of …
leads to elevated levels of phosphocholine and glycerophosphocholine in all types of …
Metabolic footprints and molecular subtypes in breast cancer
V Cappelletti, E Iorio, P Miodini, M Silvestri… - Disease …, 2017 - Wiley Online Library
Cancer treatment options are increasing. However, even among the same tumor histotype,
interpatient tumor heterogeneity should be considered for best therapeutic result …
interpatient tumor heterogeneity should be considered for best therapeutic result …
An overview of metabolomics data analysis: current tools and future perspectives
Metabolomics is a study of small molecules in the body and the associated metabolic
pathways and is considered to provide a close link between organism's genotype and …
pathways and is considered to provide a close link between organism's genotype and …
New chemical biopsy tool for spatially resolved profiling of human brain tissue in vivo
J Bogusiewicz, K Burlikowska, K Łuczykowski… - Scientific Reports, 2021 - nature.com
It is extremely challenging to perform chemical analyses of the brain, particularly in humans,
due to the restricted access to this organ. Imaging techniques are the primary approach …
due to the restricted access to this organ. Imaging techniques are the primary approach …
Principles of reproducible metabolite profiling of enriched lymphocytes in tumors and ascites from human ovarian cancer
MK Kilgour, S MacPherson, LG Zacharias, J LeBlanc… - Nature …, 2022 - nature.com
Identifying metabolites and delineating their immune-regulatory contribution in the tumor
microenvironment is an area of intense study. Interrogating metabolites and metabolic …
microenvironment is an area of intense study. Interrogating metabolites and metabolic …
Biomedical analysis of formalin-fixed, paraffin-embedded tissue samples: The Holy Grail for molecular diagnostics
More than a century ago in 1893, a revolutionary idea about fixing biological tissue
specimens was introduced by Ferdinand Blum, a German physician. Since then, a plethora …
specimens was introduced by Ferdinand Blum, a German physician. Since then, a plethora …
Metabolomics: a promising diagnostic and therapeutic implement for breast cancer
Z Chen, Z Li, H Li, Y Jiang - OncoTargets and therapy, 2019 - Taylor & Francis
Breast cancer (BC) is the most commonly diagnosed cancer among women and the leading
cause of cancer death. Despite the advent of numerous diagnosis and treatment methods in …
cause of cancer death. Despite the advent of numerous diagnosis and treatment methods in …
Effect of freezing and drying processes on the molecular traits of edible yellow mealworm
R Melis, A Braca, G Mulas, R Sanna, S Spada… - Innovative food science …, 2018 - Elsevier
Yellow mealworm (Tenebrio molitor L.) represents a highly sustainable source of proteins for
food and feed. Industrial production of mealworm meals for food and feed must count on …
food and feed. Industrial production of mealworm meals for food and feed must count on …
Improved workflow for mass spectrometry–based metabolomics analysis of the heart
DA Andres, LEA Young, S Veeranki… - Journal of Biological …, 2020 - ASBMB
MS-based metabolomics methods are powerful techniques to map the complex and
interconnected metabolic pathways of the heart; however, normalization of metabolite …
interconnected metabolic pathways of the heart; however, normalization of metabolite …