Extracellular vesicles (EVs) are lipid bilayered membrane structures released by all cells.
Most EV studies have been performed by using cell lines or body fluids, but the number of …

Activated choline metabolism is a hallmark of carcinogenesis and tumor progression, which
leads to elevated levels of phosphocholine and glycerophosphocholine in all types of …

Cancer treatment options are increasing. However, even among the same tumor histotype,
interpatient tumor heterogeneity should be considered for best therapeutic result …

Metabolomics is a study of small molecules in the body and the associated metabolic
pathways and is considered to provide a close link between organism's genotype and …

It is extremely challenging to perform chemical analyses of the brain, particularly in humans,
due to the restricted access to this organ. Imaging techniques are the primary approach …

Identifying metabolites and delineating their immune-regulatory contribution in the tumor
microenvironment is an area of intense study. Interrogating metabolites and metabolic …

More than a century ago in 1893, a revolutionary idea about fixing biological tissue
specimens was introduced by Ferdinand Blum, a German physician. Since then, a plethora …

Breast cancer (BC) is the most commonly diagnosed cancer among women and the leading
cause of cancer death. Despite the advent of numerous diagnosis and treatment methods in …

Yellow mealworm (Tenebrio molitor L.) represents a highly sustainable source of proteins for
food and feed. Industrial production of mealworm meals for food and feed must count on …

MS-based metabolomics methods are powerful techniques to map the complex and
interconnected metabolic pathways of the heart; however, normalization of metabolite …