Microglial research has advanced considerably in recent decades yet has been constrained
by a rolling series of dichotomies such as" resting versus activated" and" M1 versus M2." …

Protein misfolding and accumulation defines a prevailing feature of many
neurodegenerative disorders, finally resulting in the formation of toxic intra-and extracellular …

Abstract Alzheimer's disease (AD), an extremely common neurodegenerative disorder of the
older generation, is one of the leading causes of death globally. Besides the conventional …

This study examines the link between peripheral immune changes in perpetuation of the
Alzheimer's disease (AD) neuropathology and cognitive deficits. Our research design using …

Alzheimer's disease (AD) is the primary cause of age‐related dementia. Pathologically, AD
is characterized by synaptic loss, the accumulation of β‐amyloid peptides and neurofibrillary …

Recent studies identifying expression quantitative trait loci (eQTLs) in immune cells have
uncovered important links between disease risk alleles and gene expression trends in …

Mucosal-associated invariant T cells (MAIT) are a subset of invariant, innate-like T-cells that
are abundant in the gut lamina propria, kidney, lungs, and peripheral blood. MAIT cells are …

Aging, a common risk factor for multiple retinal degeneration diseases, is susceptible to the
tissue immune state. Our previous study suggested that a gamma-flicker light (γFL) improves …