[HTML][HTML] Vitamin D deficiency 2.0: an update on the current status worldwide

K Amrein, M Scherkl, M Hoffmann… - European journal of …, 2020 - nature.com
Vitamin D testing and the use of vitamin D supplements have increased substantially in
recent years. Currently, the role of vitamin D supplementation, and the optimal vitamin D …

New aspects of vitamin D metabolism and action—Addressing the skin as source and target

D Bikle, S Christakos - Nature Reviews Endocrinology, 2020 - nature.com
Vitamin D has a key role in stimulating calcium absorption from the gut and promoting
skeletal health, as well as many other important physiological functions. Vitamin D is …

Diagnosis and detection of sarcoidosis. An official American Thoracic Society clinical practice guideline

ED Crouser, LA Maier, KC Wilson… - American journal of …, 2020 - atsjournals.org
Background: The diagnosis of sarcoidosis is not standardized but is based on three major
criteria: a compatible clinical presentation, finding nonnecrotizing granulomatous …

[HTML][HTML] Vitamin D toxicity–a clinical perspective

E Marcinowska-Suchowierska… - Frontiers in …, 2018 - frontiersin.org
Confusion, apathy, recurrent vomiting, abdominal pain, polyuria, polydipsia, and
dehydration are the most often noted clinical symptoms of vitamin D toxicity (VDT; also …

Vitamin D assays and the definition of hypovitaminosis D: results from the First International Conference on Controversies in Vitamin D

CT Sempos, AC Heijboer, DD Bikle… - British journal of …, 2018 - Wiley Online Library
The First International Conference on Controversies in Vitamin D was held in Pisa, Italy, 14–
16 June 2017. The meeting's purpose was to address controversies in vitamin D research …

Vitamin D and sarcopenia: potential of vitamin D supplementation in sarcopenia prevention and treatment

R Uchitomi, M Oyabu, Y Kamei - Nutrients, 2020 - mdpi.com
Skeletal muscle, the largest organ in the human body, accounting for approximately 40% of
body weight, plays important roles in exercise and energy expenditure. In the elderly, there …

Vitamin D: Sources, physiological role, biokinetics, deficiency, therapeutic use, toxicity, and overview of analytical methods for detection of vitamin D and its …

J Janoušek, V Pilařová, K Macáková… - Critical reviews in …, 2022 - Taylor & Francis
Vitamin D has a well-known role in the calcium homeostasis associated with the
maintenance of healthy bones. It increases the efficiency of the intestinal absorption of …

Vitamin D: Newer concepts of its metabolism and function at the basic and clinical level

DD Bikle - Journal of the Endocrine Society, 2020 - academic.oup.com
The interest in vitamin D continues unabated with thousands of publications contributing to a
vast and growing literature each year. It is widely recognized that the vitamin D receptor …

The genetics of kidney stone disease and nephrocalcinosis

P Singh, PC Harris, DJ Sas, JC Lieske - Nature Reviews Nephrology, 2022 - nature.com
Kidney stones (also known as urinary stones or nephrolithiasis) are highly prevalent,
affecting approximately 10% of adults worldwide, and the incidence of stone disease is …

Vitamin D signaling in inflammation and cancer: Molecular mechanisms and therapeutic implications

A El-Sharkawy, A Malki - Molecules, 2020 - mdpi.com
Vitamin D and its active metabolites are important nutrients for human skeletal health. UV
irradiation of skin converts 7-dehydrocholesterol into vitamin D3, which metabolized in the …