Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series

J McDonald, J Sayers, SD Anker… - Journal of cachexia …, 2023 - Wiley Online Library
In cancer cachexia trials, measures of physical function are commonly used as endpoints.
For drug trials to obtain regulatory approval, efficacy in physical function endpoints may be …

ESPEN guidelines on nutrition in cancer patients

J Arends, P Bachmann, V Baracos, N Barthelemy… - Clinical nutrition, 2017 - Elsevier
Cancers are among the leading causes of morbidity and mortality worldwide, and the
number of new cases is expected to rise significantly over the next decades. At the same …

[HTML][HTML] Nutritional therapy in cancer patients receiving chemoradiotherapy: should we need stronger recommendations to act for improving outcomes?

P Cotogni, P Pedrazzoli, E De Waele, G Aprile… - Journal of …, 2019 - ncbi.nlm.nih.gov
One of the challenges during chemotherapy and radiotherapy is to complete the planned
cycles and doses without dose-limiting toxicity. Growing evidence clearly demonstrates the …

Patients' perception of chemotherapy side effects: Expectations, doctor–patient communication and impact on quality of life–An Italian survey

D Lorusso, E Bria, A Costantini… - European journal of …, 2017 - Wiley Online Library
Chemotherapy side effects (CSE) have a strong impact on patients' quality of life (QOL). To
assess patient perceptions of CSE, their impact on QOL and doctor–patient communication …

[HTML][HTML] Nutritional advice in older patients at risk of malnutrition during treatment for chemotherapy: a two-year randomized controlled trial

I Bourdel-Marchasson, C Blanc-Bisson, A Doussau… - PloS one, 2014 - journals.plos.org
Objective We tested the effect of dietary advice dedicated to increase intake in older patients
at risk for malnutrition during chemotherapy, versus usual care, on one-year mortality …

[HTML][HTML] Impact of home enteral nutrition in malnourished patients with upper gastrointestinal cancer: a multicentre randomised clinical trial

C Gavazzi, S Colatruglio, F Valoriani… - European Journal of …, 2016 - Elsevier
Background Weight loss is frequent in patients with gastrointestinal (GI) cancer. Nutritional
status deteriorates throughout anti-cancer treatment, mostly after major surgery, increasing …

Maintenance of the nutritional prognostic index predicts survival in patients with unresectable metastatic colorectal cancer

T Ikeya, M Shibutani, K Maeda, K Sugano… - Journal of cancer …, 2015 - Springer
Purpose Nutrition and immunity significantly affect the progression of cancer in cancer
patients. Therefore, the evaluation of the nutritional and immune status would be useful as a …

[HTML][HTML] Nutritional and inflammatory measures predict survival of patients with stage IV colorectal cancer

Y Takamizawa, D Shida, N Boku, Y Nakamura, Y Ahiko… - BMC cancer, 2020 - Springer
Background This study aimed to evaluate the prognostic impact of nutritional and
inflammatory measures (controlling nutritional status (CONUT) score, prognostic nutritional …

Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series

OM Vagnildhaug, TR Balstad, I Ottestad… - Journal of Cachexia …, 2024 - Wiley Online Library
There is no consensus on the optimal endpoint (s) in cancer cachexia trials. Endpoint
variation is an obstacle when comparing interventions and their clinical value. The aim of …

[HTML][HTML] Psychosocial support in cancer cachexia syndrome: the evidence for supported self-management of eating problems during radiotherapy or chemotherapy …

J Hopkinson - Asia-Pacific Journal of Oncology Nursing, 2018 - Elsevier
People receiving cancer treatment are at nutritional risk. Their eating problems can lead to
malnutrition and weight loss. Involuntary weight loss is also a defining characteristic of tumor …