Co-delivery of paclitaxel and survivin shRNA by pluronic P85-PEI/TPGS complex nanoparticles to overcome drug resistance in lung cancer
J Shen, Q Yin, L Chen, Z Zhang, Y Li - Biomaterials, 2012 - Elsevier
Drug resistance is a main obstacle for the successful chemotherapy of lung cancer. In this
work, a new co-delivery system, P85-PEI/TPGS/PTX/shSur complex nanoparticles (PTPNs) …
work, a new co-delivery system, P85-PEI/TPGS/PTX/shSur complex nanoparticles (PTPNs) …
[PDF][PDF] Effect of aspartame on some oxidative stress parameters in liver and kidney of rats
MM Iman - Afr J Pharm Pharmacol, 2011 - academicjournals.org
Aspartame is one of the most widely used artificial sweeteners in over 90 countries
worldwide. It is a highly intensity sweetener added to a large variety of food, most commonly …
worldwide. It is a highly intensity sweetener added to a large variety of food, most commonly …
Enhancement of oxaliplatin sensitivity in human colorectal cancer by hypericin mediated photodynamic therapy via ROS-related mechanism
S Lin, K Lei, W Du, L Yang, H Shi, Y Gao, P Yin… - … International Journal of …, 2016 - Elsevier
The resistance to oxaliplatin (L-OHP) is a major obstacle to ideal therapeutic outcomes in
colorectal cancer. Photodynamic therapy (PDT) induces tumor damage through …
colorectal cancer. Photodynamic therapy (PDT) induces tumor damage through …
Long-term effect of aspartame on the liver antioxidant status and histopathology in Wistar albino rats
The use of the artificial sweetener aspartame has long been contemplated and studied by
researcher around the world regarding their varying negative effects. The present study aims …
researcher around the world regarding their varying negative effects. The present study aims …
Bioactivation of luteolin by tyrosinase selectively inhibits glutathione S-transferase
R Balyan, SK Kudugunti, HA Hamad, MS Yousef… - Chemico-biological …, 2015 - Elsevier
Glutathione S-transferase (GST) plays a significant role in the metabolism and detoxification
of drugs used in treatment of melanoma, resulting in a decrease in drug efficacy. Tyrosinase …
of drugs used in treatment of melanoma, resulting in a decrease in drug efficacy. Tyrosinase …
Hypericin as a potential drug for treating Alzheimer's disease and type 2 diabetes with a view to drug repositioning
X Yuan, F Yan, LH Gao, QH Ma… - CNS Neuroscience & …, 2023 - Wiley Online Library
Aims Alzheimer's disease (AD) and type 2 diabetes (T2D) are two of the most common
diseases in elderly population and they have a high rate of comorbidity. Study has revealed …
diseases in elderly population and they have a high rate of comorbidity. Study has revealed …
The metabolic bioactivation of caffeic acid phenethyl ester (CAPE) mediated by tyrosinase selectively inhibits glutathione S-transferase
SK Kudugunti, H Thorsheim, MS Yousef, L Guan… - Chemico-biological …, 2011 - Elsevier
Glutathione S-transferase (GST) and multidrug resistance-associated proteins (MRPs) play
major roles in drug resistance in melanoma. In this study, we investigated caffeic acid …
major roles in drug resistance in melanoma. In this study, we investigated caffeic acid …
[PDF][PDF] Alterations in antioxidant defense system in hepatic and renal tissues of rats following aspartame intake
SA Alwaleedi - J Appl Biol Biotechnol, 2016 - pdfs.semanticscholar.org
Aspartame is one of the most common artificial sweeteners in use today worldwide.
Aspartame has been implicated in many health problems. The study aimed to investigate …
Aspartame has been implicated in many health problems. The study aimed to investigate …
Amitriptyline may have a supportive role in cancer treatment by inhibiting glutathione S-transferase pi (GST-π) and alpha (GST-α)
G Kulaksiz-Erkmen, O Dalmizrak… - Journal of enzyme …, 2013 - Taylor & Francis
A tricyclic anti-depressant, amitriptyline, is a highly prescribed drug for cancer patients for
mood elevation but there are limited studies about the interaction of amitriptyline with …
mood elevation but there are limited studies about the interaction of amitriptyline with …
The inhibition characteristics of human placental glutathione S-transferase-π by tricyclic antidepressants: amitriptyline and clomipramine
O Dalmizrak, G Kulaksiz-Erkmen, N Ozer - Molecular and cellular …, 2011 - Springer
Tricyclic antidepressants (TCAs) are the non-selective amine re-uptake inhibitors, well
absorbed from small intestine, cross the blood–brain barrrier, distributed in the brain, and …
absorbed from small intestine, cross the blood–brain barrrier, distributed in the brain, and …