Gastric cancer is one of the most aggressive malignancies, with limited treatment options in
both locally advanced and metastatic setting, resulting in poor prognosis. Based on genomic …

Background Several associations between microsatellite instability (MSI) and other
clinicopathological factors have been reported in gastric cancer, but the results have been …

Gastric cancer remains highly prevalent and accounts for a notable proportion of global
cancer mortality. This cancer is also associated with poor survival rates. Understanding the …

Gastric cancer (GC), a heterogeneous disease characterized by epidemiologic and
histopathologic differences across countries, is a leading cause of cancer-related death …

More than 1.6 million new cases of cancer will be diagnosed in the US in 2016, resulting in
more than 500,000 deaths. Although chemotherapy has been the mainstay of treatment in …

Defects in the DNA mismatch repair (MMR) proteins, result in a phenotype called
microsatellite instability (MSI), occurring in up to 15% of sporadic colorectal cancers …

Esophageal and gastric cancers represent tumors with poor prognosis. Unfortunately,
radiotherapy, chemotherapy, and targeted therapy have made only limited progress in …

Gastric cancers with mismatch repair (MMR) inactivation are characterised by microsatellite
instability (MSI). In this study, the transcriptional profile of 38 gastric cancers with and without …

Although surgical resection is the standard curative therapy for gastric cancer, these tumors
are often diagnosed at an advanced stage, when surgery is not recommended. Alternative …

Microsatellite instable gastric cancer (MSI-GC) is a specific molecular subtype of GC. We
studied the phenotypes, genotypes, and clinicopathologic characteristics of MSI-GC in a …