Size-based separation methods of circulating tumor cells

SJ Hao, Y Wan, YQ Xia, X Zou, SY Zheng - Advanced drug delivery reviews, 2018 - Elsevier
Circulating tumor cells (CTCs) originate from the primary tumor mass and enter into the
peripheral bloodstream. Compared to other “liquid biopsy” portfolios such as exosome …

[HTML][HTML] Circulating tumour cells: the evolving concept and the inadequacy of their enrichment by EpCAM-based methodology for basic and clinical cancer research

PK Grover, AG Cummins, TJ Price… - Annals of …, 2014 - Elsevier
Increasing evidence suggests that circulating tumour cells (CTCs) are responsible for
metastatic relapse and this has fuelled interest in their detection and quantification. Although …

Rapid isolation of cancer cells using microfluidic deterministic lateral displacement structure

Z Liu, F Huang, J Du, W Shu, H Feng, X Xu, Y Chen - Biomicrofluidics, 2013 - pubs.aip.org
This work reports a microfluidic device with deterministic lateral displacement (DLD) arrays
allowing rapid and label-free cancer cell separation and enrichment from diluted peripheral …

[HTML][HTML] Prognostic impact of circulating tumor cells in patients with small cell lung cancer

T Naito, F Tanaka, A Ono, K Yoneda… - Journal of Thoracic …, 2012 - Elsevier
Background Enumeration of circulating tumor cells (CTCs) may be valuable for prognostic
assessment in lung cancer patients. In this study, we report the clinical significance of CTCs …

[HTML][HTML] CTC enumeration and characterization: moving toward personalized medicine

A Toss, Z Mu, S Fernandez… - Annals of translational …, 2014 - ncbi.nlm.nih.gov
The primary cause of tumor-related death in breast cancer (BC) is still represented by distant
metastasization. The dissemination of tumor cells from the primary tumor to distant sites …

[HTML][HTML] Circulating tumor cells: finding the needle in the haystack

X Zhe, ML Cher, RD Bonfil - American journal of cancer research, 2011 - ncbi.nlm.nih.gov
Localized and metastatic cancers give rise to circulating tumor cells (CTCs) which are
detectable in the bloodstream. Recent studies have highlighted the prognostic significance …

Interleukin-1β promotes skeletal colonization and progression of metastatic prostate cancer cells with neuroendocrine features

Q Liu, MR Russell, K Shahriari, DL Jernigan, MI Lioni… - Cancer research, 2013 - AACR
Despite the progress made in the early detection and treatment of prostate adenocarcinoma,
the metastatic lesions from this tumor are incurable. We used genome-wide expression …

Fourier ptychographic microscopy for filtration-based circulating tumor cell enumeration and analysis

A Williams, J Chung, X Ou, G Zheng… - … of biomedical optics, 2014 - spiedigitallibrary.org
Circulating tumor cells (CTCs) are recognized as a candidate biomarker with strong
prognostic and predictive potential in metastatic disease. Filtration-based enrichment …

Circulating tumor cells: strategies for capture, analyses, and propagation

A Agarwal, M Balic, D El-Ashry, RJ Cote - The Cancer Journal, 2018 - journals.lww.com
Circulating tumor cells (CTCs) play a central role in tumor dissemination and metastases,
which are ultimately responsible for most cancer deaths. Technologies that allow for …

Novel small-molecule CX3CR1 antagonist impairs metastatic seeding and colonization of breast cancer cells

F Shen, Y Zhang, DL Jernigan, X Feng, J Yan… - Molecular Cancer …, 2016 - AACR
Recent evidence indicates that cancer cells, even in the absence of a primary tumor,
recirculate from established secondary lesions to further seed and colonize skeleton and …