Size-based separation methods of circulating tumor cells
Circulating tumor cells (CTCs) originate from the primary tumor mass and enter into the
peripheral bloodstream. Compared to other “liquid biopsy” portfolios such as exosome …
peripheral bloodstream. Compared to other “liquid biopsy” portfolios such as exosome …
[HTML][HTML] Circulating tumour cells: the evolving concept and the inadequacy of their enrichment by EpCAM-based methodology for basic and clinical cancer research
PK Grover, AG Cummins, TJ Price… - Annals of …, 2014 - Elsevier
Increasing evidence suggests that circulating tumour cells (CTCs) are responsible for
metastatic relapse and this has fuelled interest in their detection and quantification. Although …
metastatic relapse and this has fuelled interest in their detection and quantification. Although …
Rapid isolation of cancer cells using microfluidic deterministic lateral displacement structure
This work reports a microfluidic device with deterministic lateral displacement (DLD) arrays
allowing rapid and label-free cancer cell separation and enrichment from diluted peripheral …
allowing rapid and label-free cancer cell separation and enrichment from diluted peripheral …
[HTML][HTML] Prognostic impact of circulating tumor cells in patients with small cell lung cancer
T Naito, F Tanaka, A Ono, K Yoneda… - Journal of Thoracic …, 2012 - Elsevier
Background Enumeration of circulating tumor cells (CTCs) may be valuable for prognostic
assessment in lung cancer patients. In this study, we report the clinical significance of CTCs …
assessment in lung cancer patients. In this study, we report the clinical significance of CTCs …
[HTML][HTML] CTC enumeration and characterization: moving toward personalized medicine
A Toss, Z Mu, S Fernandez… - Annals of translational …, 2014 - ncbi.nlm.nih.gov
The primary cause of tumor-related death in breast cancer (BC) is still represented by distant
metastasization. The dissemination of tumor cells from the primary tumor to distant sites …
metastasization. The dissemination of tumor cells from the primary tumor to distant sites …
[HTML][HTML] Circulating tumor cells: finding the needle in the haystack
Localized and metastatic cancers give rise to circulating tumor cells (CTCs) which are
detectable in the bloodstream. Recent studies have highlighted the prognostic significance …
detectable in the bloodstream. Recent studies have highlighted the prognostic significance …
Interleukin-1β promotes skeletal colonization and progression of metastatic prostate cancer cells with neuroendocrine features
Q Liu, MR Russell, K Shahriari, DL Jernigan, MI Lioni… - Cancer research, 2013 - AACR
Despite the progress made in the early detection and treatment of prostate adenocarcinoma,
the metastatic lesions from this tumor are incurable. We used genome-wide expression …
the metastatic lesions from this tumor are incurable. We used genome-wide expression …
Fourier ptychographic microscopy for filtration-based circulating tumor cell enumeration and analysis
Circulating tumor cells (CTCs) are recognized as a candidate biomarker with strong
prognostic and predictive potential in metastatic disease. Filtration-based enrichment …
prognostic and predictive potential in metastatic disease. Filtration-based enrichment …
Circulating tumor cells: strategies for capture, analyses, and propagation
Circulating tumor cells (CTCs) play a central role in tumor dissemination and metastases,
which are ultimately responsible for most cancer deaths. Technologies that allow for …
which are ultimately responsible for most cancer deaths. Technologies that allow for …
Novel small-molecule CX3CR1 antagonist impairs metastatic seeding and colonization of breast cancer cells
F Shen, Y Zhang, DL Jernigan, X Feng, J Yan… - Molecular Cancer …, 2016 - AACR
Recent evidence indicates that cancer cells, even in the absence of a primary tumor,
recirculate from established secondary lesions to further seed and colonize skeleton and …
recirculate from established secondary lesions to further seed and colonize skeleton and …