Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Recent advances of optical imaging in the second near‐infrared window

Kenry, Y Duan, B Liu - Advanced materials, 2018 - Wiley Online Library
The near‐infrared window between 1000 and 1700 nm, commonly termed the “second near‐
infrared (NIR‐II) window,” has quickly emerged as a highly attractive optical region for …

Fluorescent chemical probes for accurate tumor diagnosis and targeting therapy

M Gao, F Yu, C Lv, J Choo, L Chen - Chemical Society Reviews, 2017 - pubs.rsc.org
Surgical resection of solid tumors is currently the gold standard and preferred therapeutic
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …

Shortwave infrared fluorescence imaging with the clinically approved near-infrared dye indocyanine green

JA Carr, D Franke, JR Caram… - Proceedings of the …, 2018 - National Acad Sciences
Fluorescence imaging is a method of real-time molecular tracking in vivo that has enabled
many clinical technologies. Imaging in the shortwave IR (SWIR; 1,000–2,000 nm) promises …

Large Stokes shift benzothiazolium cyanine dyes with improved intramolecular charge transfer (ICT) for cell imaging applications

CS Abeywickrama - Chemical Communications, 2022 - pubs.rsc.org
Intramolecular Charge Transfer (ICT) is a crucial photophysical phenomenon that can be
used to improve the Stokes' shift in fluorescent dyes. The introduction of molecular …

Design of one-for-all near-infrared aggregation-induced emission nanoaggregates for boosting theranostic efficacy

H Xie, Z Bi, J Yin, Z Li, L Hu, C Zhang, J Zhang… - ACS …, 2023 - ACS Publications
Fluorescence-guided phototherapy, including photodynamic and photothermal therapy, is
considered an emerging noninvasive strategy for cancer treatments. Organic molecules are …

Optical biosensors for virus detection: prospects for SARS‐CoV‐2/COVID‐19

H Maddali, CE Miles, J Kohn, DM O'Carroll - ChemBioChem, 2021 - Wiley Online Library
The recent pandemic of the novel coronavirus disease 2019 (COVID‐19) has caused huge
worldwide disruption due to the lack of available testing locations and equipment. The use of …

Application of the nano-drug delivery system in treatment of cardiovascular diseases

Y Deng, X Zhang, H Shen, Q He, Z Wu… - … in bioengineering and …, 2020 - frontiersin.org
Cardiovascular diseases (CVDs) have become a serious threat to human life and health.
Though many drugs acting via different mechanism of action are available in the market as …

Image-guided cancer surgery using near-infrared fluorescence

AL Vahrmeijer, M Hutteman, JR Van Der Vorst… - Nature reviews Clinical …, 2013 - nature.com
Paradigm shifts in surgery arise when surgeons are empowered to perform surgery faster,
better and less expensively than current standards. Optical imaging that exploits invisible …

Challenges and key considerations of the enhanced permeability and retention effect for nanomedicine drug delivery in oncology

U Prabhakar, H Maeda, RK Jain, EM Sevick-Muraca… - 2013 - AACR
Enhanced permeability of the tumor vasculature allows macromolecules to enter the tumor
interstitial space, whereas the suppressed lymphatic filtration allows them to stay there. This …