[HTML][HTML] Sex and gender differences in Alzheimer's disease dementia

MM Mielke - The Psychiatric times, 2018 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) dementia is the most common form of dementia, comprising 60 to
70 percent of all cases. AD is a progressive neurodegenerative disease that causes memory …

Clinical epidemiology of Alzheimer's disease: assessing sex and gender differences

MM Mielke, P Vemuri, WA Rocca - Clinical epidemiology, 2014 - Taylor & Francis
With the aging of the population, the burden of Alzheimer's disease (AD) is rapidly
expanding. More than 5 million people in the US alone are affected with AD and this number …

Differences between women and men in incidence rates of dementia and Alzheimer's disease

CR Beam, C Kaneshiro, JY Jang… - Journal of …, 2018 - content.iospress.com
In the following brief report, we examined gender differences in incidence rates of any
dementia, Alzheimer's disease (AD) alone, and non-Alzheimer's dementia alone in 16,926 …

Prevalence of biologically vs clinically defined Alzheimer spectrum entities using the National Institute on Aging–Alzheimer's Association research framework

CR Jack, TM Therneau, SD Weigand, HJ Wiste… - JAMA …, 2019 - jamanetwork.com
Importance A National Institute on Aging–Alzheimer's Association (NIA-AA) workgroup
recently published a research framework in which Alzheimer disease is defined by …

Dementia in western Europe: epidemiological evidence and implications for policy making

YT Wu, L Fratiglioni, FE Matthews, A Lobo… - The Lancet …, 2016 - thelancet.com
Dementia is receiving increasing attention from governments and politicians.
Epidemiological research based on western European populations done 20 years ago …

Sex differences in Alzheimer's disease and common neuropathologies of aging

S Oveisgharan, Z Arvanitakis, L Yu, J Farfel… - Acta …, 2018 - Springer
Alzheimer's dementia is significantly more common in women than in men. However, few
pathological studies have addressed sex difference in Alzheimer's disease (AD) and other …

Epidemiology of Alzheimer disease

R Mayeux, Y Stern - Cold Spring Harbor …, 2012 - perspectivesinmedicine.cshlp.org
The global prevalence of dementia has been estimated to be as high as 24 million, and is
predicted to double every 20 years until at least 2040. As the population worldwide …

Neuroimmunology and neuroepigenetics in the establishment of sex differences in the brain

MM McCarthy, BM Nugent, KM Lenz - Nature Reviews Neuroscience, 2017 - nature.com
The study of sex differences in the brain is a topic of neuroscientific study that has broad
reaching implications for culture, society and biomedical science. Recent research in rodent …

Higher risk of progression to dementia in mild cognitive impairment cases who revert to normal

RO Roberts, DS Knopman, MM Mielke, RH Cha… - Neurology, 2014 - AAN Enterprises
Objective: To estimate rates of progression from mild cognitive impairment (MCI) to dementia
and of reversion from MCI to being cognitively normal (CN) in a population-based cohort …

Estrogen: a master regulator of bioenergetic systems in the brain and body

JR Rettberg, J Yao, RD Brinton - Frontiers in neuroendocrinology, 2014 - Elsevier
Estrogen is a fundamental regulator of the metabolic system of the female brain and body.
Within the brain, estrogen regulates glucose transport, aerobic glycolysis, and mitochondrial …