Regeneration is the process of replacing/restoring a damaged cell/tissue/organ to its full
function and is limited respecting complexity of specific organ structures and the level of …

Astrocytes, through their close associations with synapses, can monitor and alter synaptic
function, thus actively controlling synaptic transmission in the adult brain. Besides their …

The classic view of sensorineural hearing loss (SNHL) is that the “primary” targets are hair
cells, and that cochlear-nerve loss is “secondary” to hair cell degeneration. Our recent work …

Astrocytes are now emerging as key participants in many aspects of brain development,
function and disease. In particular, new evidence shows that astrocytes powerfully control …

Astrocytes, oligodendrocytes, and microglia are abundant cell types found in the central
nervous system and have been shown to play crucial roles in regulating both normal and …

Traumatic brain injury (TBI) is one of the leading causes of fatality and disability worldwide.
Despite its high prevalence, effective treatment strategies for TBI are limited. Traumatic brain …

Astrocytes are highly specialized glial cells responsible for trophic and metabolic support of
neurons. They are associated to ionic homeostasis, the regulation of cerebral blood flow and …

Highlights•Astrocytes secrete synaptogenic factors to induce synapse formation.•Astrocytes
control formation of specific synapses to build different circuits.•Astrocyte heterogeneity …

Neurotrophin-3 (Ntf3) and brain derived neurotrophic factor (Bdnf) are critical for sensory
neuron survival and establishment of neuronal projections to sensory epithelia in the …

In acquired sensorineural hearing loss, such as that produced by noise or aging, there can
be massive loss of the synaptic connections between cochlear sensory cells and primary …