Mechanisms of nanoparticle transport across intestinal tissue: an oral delivery perspective

SA Ejazi, R Louisthelmy, K Maisel - ACS nano, 2023 - ACS Publications
Oral drug administration has been a popular choice due to patient compliance and limited
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …

Lipid-based nanoparticles as a pivotal delivery approach in triple negative breast cancer (TNBC) therapy

A Chaudhuri, DN Kumar, RA Shaik, BG Eid… - International journal of …, 2022 - mdpi.com
Triple-negative breast cancer is considered the most aggressive type of breast cancer
among women and the lack of expressed receptors has made treatment options …

[HTML][HTML] Current status of nanoscale drug delivery and the future of nano-vaccine development for leishmaniasis–A review

P Prasanna, P Kumar, S Kumar, VK Rajana… - Biomedicine & …, 2021 - Elsevier
The study of tropical diseases like leishmaniasis, a parasitic disease, has not received much
attention even though it is the second-largest infectious disease after malaria. As per the …

Immunotherapy and immunochemotherapy in combating visceral leishmaniasis

G Yadagiri, A Singh, K Arora, SL Mudavath - Frontiers in Medicine, 2023 - frontiersin.org
Visceral leishmaniasis (VL), a vector-borne disease, is caused by an obligate
intramacrophage, kinetoplastid protozoan parasite of the genus Leishmania. Globally, VL is …

Corneal targeted fenticonazole nitrate-loaded novasomes for the management of ocular candidiasis: Preparation, in vitro characterization, ex vivo and in vivo …

S Ahmed, MM Amin, SM El-Korany, S Sayed - Drug Delivery, 2022 - Taylor & Francis
The purpose of this manuscript was to develop and optimize Fenticonazole Nitrate (FTN)-
loaded novasomes aiming to enhance drug corneal penetration and to improve its …

[HTML][HTML] Current challenges and nanotechnology-based pharmaceutical strategies for the treatment and control of malaria

L Gujjari, H Kalani, SK Pindiprolu… - Parasite Epidemiology …, 2022 - Elsevier
Malaria is one of the prevalent tropical diseases caused by the parasitic protozoan of the
genus Plasmodium spp. With an estimated 228 million cases, it is a major public health …

Ultra-deformable free fatty acid based nano-carriers for topical delivery of Luteolin: A potential paradigm for management of Methicillin-Resistant Staphylococcus …

MY Zakaria, WA Eraqi, SA Mohamed - International Journal of …, 2023 - Elsevier
The incidences of antimicrobial resistance in particular, Methicillin-Resistant Staphylococcus
aureus (MRSA) have increased during the last two decades. However, conventional dosage …

Lipid Nanoparticles: An Effective Tool to Improve the Bioavailability of Nutraceuticals

R Ashfaq, A Rasul, S Asghar, A Kovács… - International Journal of …, 2023 - mdpi.com
Nano-range bioactive colloidal carrier systems are envisaged to overcome the challenges
associated with treatments of numerous diseases. Lipid nanoparticles (LNPs), one of the …

Potential lipid-based strategies of amphotericin B designed for oral administration in clinical application

X Zhong, J Yang, H Liu, Z Yang, P Luo - Drug Delivery, 2023 - Taylor & Francis
Amphotericin B (AmB) is regarded as a first-line therapy against life-threatening invasive
fungal infections. Due to its poor oral bioavailability, AmB is restricted to intravenous …

Carboxymethyl chitosan modified lipid nanoformulations as a highly efficacious and biocompatible oral anti-leishmanial drug carrier system

A Singh, G Yadagiri, M Negi, AK Kushwaha… - International Journal of …, 2022 - Elsevier
Herein, carboxymethyl chitosan (CMC) grafted lipid nanoformulations were facilely prepared
by thin-film hydration method as a highly efficient biocompatible anti-leishmanial carrier …