The process of formulating a good research question can be challenging and frustrating.
While a comprehensive literature review is compulsory, the researcher usually encounters …

Introduction: This article, derived from a Technical Brief prepared for the Agency for
Healthcare Research and Quality, presents an overview on current models of care for …

A well-formulated research question should incorporate the components of a 'problem', an
'intervention', a 'control', and an 'outcome'—at least according to the PICO mnemonic. The …

Background The first steps of any study are developing the research question, aim and
objective. Subsequent steps develop from these and they govern the researchers' choice of …

In vitro pre-clinical research is an important aspect of the development of new dental
materials and techniques, because it can provide essential information for further testing of …

Addressing a sample size is a practical issue that has to be solved during planning and
designing stage of the study. The aim of any clinical research is to detect the actual …

The use of real-world data (RWD) for generating real-world evidence (RWE) to complement
interventional clinical trial-based research is rapidly increasing. This evolving field is …

Stakeholders in healthcare are increasingly turning to real world evidence (RWE) to inform
their decisions, alongside evidence from randomized controlled trials. RWE is generated by …

Objectives: To compare the impact of immediate and delayed implant placement upon the
survival of implants and to investigate the differences in implant survival between immediate …

Background The prevalence of osteoporotic vertebral body fractures in Europe is 18–26%.
Although most of these injuries can be treated conservatively, the underlying concepts have …