[HTML][HTML] Role of fibrinolytic enzymes in anti-thrombosis therapy
F Altaf, S Wu, V Kasim - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Thrombosis, a major cause of deaths in this modern era responsible for 31% of all global
deaths reported by WHO in 2017, is due to the aggregation of fibrin in blood vessels which …
deaths reported by WHO in 2017, is due to the aggregation of fibrin in blood vessels which …
[HTML][HTML] Microbial therapeutic enzymes: A promising area of biopharmaceuticals
Biopharmaceuticals is a rapidly emerging field that explores and employs biological
organisms and their products for therapeutic applications. Enzymes are remarkable …
organisms and their products for therapeutic applications. Enzymes are remarkable …
[HTML][HTML] Thrombolytic enzymes of microbial origin: a review
D Diwan, Z Usmani, M Sharma, JW Nelson… - International journal of …, 2021 - mdpi.com
Enzyme therapies are attracting significant attention as thrombolytic drugs during the current
scenario owing to their great affinity, specificity, catalytic activity, and stability. Among various …
scenario owing to their great affinity, specificity, catalytic activity, and stability. Among various …
Use of exogenous enzymes in human therapy: approved drugs and potential applications
P Cioni, E Gabellieri, B Campanini… - Current Medicinal …, 2022 - ingentaconnect.com
The development of safe and efficacious enzyme-based human therapies has increased
greatly in the last decades, thanks to remarkable advances in the understanding of the …
greatly in the last decades, thanks to remarkable advances in the understanding of the …
Efficacy and safety of a bolus of half-dose R-SAK prior to primary PCI in ST-elevation myocardial infarction: Rationale and design of the optima-6 trial
C Li, JW Eikelboom, Z Zhong, X Zhang, K Liu… - American Heart …, 2023 - Elsevier
Background Time to reperfusion is the key to the treatment of patients with ST-elevation
myocardial infarction (STEMI). It is uncertain whether adjunctive thrombolytic therapy …
myocardial infarction (STEMI). It is uncertain whether adjunctive thrombolytic therapy …
[HTML][HTML] CcpA Regulates Staphylococcus aureus Biofilm Formation through Direct Repression of Staphylokinase Expression
M Zheng, K Zhu, H Peng, W Shang, Y Zhao, S Lu… - Antibiotics, 2022 - mdpi.com
Staphylococcus aureus represents a notorious opportunistic pathogen causing various
infections in biofilm nature, imposing remarkable therapeutic challenges worldwide. The …
infections in biofilm nature, imposing remarkable therapeutic challenges worldwide. The …
Recent trends in targeted delivery of smart nanocarrier-based microbial enzymes for therapeutic applications
Smart carrier-based immobilization has widened the use of enzymes for the treatment of
several disorders. Large surface areas, tunable morphology, and surface modification ability …
several disorders. Large surface areas, tunable morphology, and surface modification ability …
Engineered Microrobots for Targeted Delivery of Bacterial Outer Membrane Vesicles (OMV) in Thrombus Therapy
In the realm of thrombosis treatment, bioengineered outer membrane vesicles (OMVs) offer
a novel and promising approach, as they have rich content of bacterial‐derived components …
a novel and promising approach, as they have rich content of bacterial‐derived components …
Platelet Membrane-Coated r-SAK Improves Thrombolytic Efficacy by Targeting Thrombus
R Hua, M Li, Q Lin, M Dong, X Gong, Z Lin… - … Applied Materials & …, 2024 - ACS Publications
Thrombolytic therapy is one of the most effective treatments for thrombus dissolution and
recanalization of blocked vessels in thrombotic diseases. However, the application of the …
recanalization of blocked vessels in thrombotic diseases. However, the application of the …
Macroalgae: Marine players in vaccinology
Although seaweeds have been used for decades as food, medicinal plants, and nutritional
supplements, their use as a vaccine production and delivery platform has been barely …
supplements, their use as a vaccine production and delivery platform has been barely …