Prion diseases range from being highly infectious, for example scrapie and CWD which
show facile transmission between susceptible individuals, to showing negligible horizontal …

Simple Summary Classical scrapie is a prionic, neurological, consumptive, and chronic
disease that affects naturally domestic small ruminants. It was initially described in the UK …

A major problem for the effective diagnosis and management of prion diseases is the lack of
rapid high-throughput assays to measure low levels of prions. Such measurements have …

Key to understanding the epidemiology and pathogenesis of prion diseases, including
chronic wasting disease (CWD) of cervids, is determining the mode of transmission from one …

Soil behaves as a medium of biogeochemical transformations and fluxes and comprises
mineral, gaseous, liquid and biological components that have direct impacts on human …

Efficient horizontal transmission is a signature trait of chronic wasting disease (CWD) in
cervids. Infectious prions shed into excreta appear to play a key role in this facile …

ABSTRACT A key challenge in managing transmissible spongiform encephalopathies
(TSEs) or prion diseases in medicine, agriculture, and wildlife biology is the development of …

Chronic wasting disease (CWD) is an emergent, rapidly spreading prion disease of cervids.
Shedding of infectious prions in saliva and urine is thought to be an important factor in CWD …

Background Chronic wasting disease (CWD) is a prion disease affecting members of the
Cervidae family. PrP C primary structures play a key role in CWD susceptibility resulting in …

Prion diseases are sub-acute neurodegenerative diseases that affect humans and some
domestic and free-ranging animals. Infectious prion agents are considered to comprise …