Toolbox for distal C–H bond functionalizations in organic molecules

SK Sinha, S Guin, S Maiti, JP Biswas, S Porey… - Chemical …, 2021 - ACS Publications
Transition-metal-catalyzed C–H activation has developed a contemporary approach to the
omnipresent area of retrosynthetic disconnection. Scientific researchers have been tempted …

Carboxylic acids as adaptive functional groups in metallaphotoredox catalysis

SB Beil, TQ Chen, NE Intermaggio… - Accounts of chemical …, 2022 - ACS Publications
Conspectus The development of palladium-catalyzed cross-coupling methods for the
activation of C (sp2)–Br bonds facilitated access to arene-rich molecules, enabling a …

Carbon–Carbon Bond Cleavage for Late-Stage Functionalization

YF Liang, M Bilal, LY Tang, TZ Wang, YQ Guan… - Chemical …, 2023 - ACS Publications
Late-stage functionalization (LSF) introduces functional group or structural modification at
the final stage of the synthesis of natural products, drugs, and complex compounds. It is …

Photoelectrochemical asymmetric catalysis enables direct and enantioselective decarboxylative cyanation

XL Lai, M Chen, Y Wang, J Song… - Journal of the American …, 2022 - ACS Publications
The development of efficient and sustainable methods for decarboxylative transformations is
of great importance due to the ease of availability and nontoxicity of carboxylic acids …

Photoinduced borylation for the synthesis of organoboron compounds: focus review

YM Tian, XN Guo, H Braunschweig, U Radius… - Chemical …, 2021 - ACS Publications
Organoboron compounds have important synthetic value and can be applied in numerous
transformations. The development of practical and convenient ways to synthesize boronate …

3d transition metals for C–H activation

P Gandeepan, T Müller, D Zell, G Cera… - Chemical …, 2018 - ACS Publications
C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with
notable applications to material sciences, crop protection, drug discovery, and …

Transition-metal catalyzed C–H activation as a means of synthesizing complex natural products

SK Sinha, P Ghosh, S Jain, S Maiti… - Chemical Society …, 2023 - pubs.rsc.org
Over the past few decades, the advent of C–H activation has led to a rethink among
chemists about the synthetic strategies employed for multi-step transformations. Indeed …

[HTML][HTML] A comprehensive overview of directing groups applied in metal-catalysed C–H functionalisation chemistry

C Sambiagio, D Schönbauer, R Blieck… - Chemical Society …, 2018 - pubs.rsc.org
The present review is devoted to summarizing the recent advances (2015–2017) in the field
of metal-catalysed group-directed C–H functionalisation. In order to clearly showcase the …

Transition-metal-catalyzed cross-couplings through carbene migratory insertion

Y Xia, D Qiu, J Wang - Chemical reviews, 2017 - ACS Publications
Transition-metal-catalyzed cross-coupling reactions have been well-established as
indispensable tools in modern organic synthesis. One of the major research goals in cross …

Enantioselective C− H Activation with Earth‐Abundant 3d Transition Metals

J Loup, U Dhawa, F Pesciaioli… - Angewandte Chemie …, 2019 - Wiley Online Library
Molecular syntheses largely rely on time‐and labour‐intensive prefunctionalization
strategies. In contrast, C− H activation represents an increasingly powerful approach that …