[HTML][HTML] Recent Technologies towards Diagnostic and Therapeutic Applications of Circulating Nucleic Acids in Colorectal Cancers

J Chung, S Xiao, Y Gao, YH Soung - International Journal of Molecular …, 2024 - mdpi.com
Liquid biopsy has emerged as a promising noninvasive approach for colorectal cancer
(CRC) management. This review focuses on technologies detecting circulating nucleic …

[HTML][HTML] Quantitative detection of circular RNA and microRNA at point-of-care using droplet digital CRISPR/Cas13a platform

K Wang, H Yin, S Li, Y Wan, M Xiao, X Yuan… - Biosensors and …, 2025 - Elsevier
Circular RNA (circRNA) and microRNA (miRNA) are both non-coding RNAs (ncRNAs) that
serve as biomarkers for cancer diagnosis and prognosis. Quantitative detection of these …

[HTML][HTML] based screen-printed electrode to detect miRNA-652 associated to triple-negative breast cancer

A Raucci, W Cimmino, SP Grosso, N Normanno… - Electrochimica …, 2024 - Elsevier
Triple-negative breast cancer (TNBC) is one of the most aggressive and lethal types of BC,
affecting mostly young women and its diagnosis is difficult and requires invasive methods …

[HTML][HTML] Transformative approaches for siRNA detection

S Singh, A Raucci, W Cimmino, A Miglione… - OpenNano, 2024 - Elsevier
Small interfering RNA (siRNA) is essential for the process of gene silencing, especially for
cancer. Despite its considerable promise, siRNA faces challenges due to stability issues of …

GOX mediated oxygen tolerance ATRP for detection of esophageal cancer biomarker miRNA-144

N Ma, W Qiu, G Wei, J Zhang, H Yu, J Kong… - Chemical Engineering …, 2024 - Elsevier
The novel enzyme cascade biosensor described here involves glucose oxidase (GOX)
mediated and FADH 2 production under specific blue wavelengths to facilitate …

AI-Enhanced Visual-Spectral Synergy for Fast and Ultrasensitive Biodetection of Breast Cancer-Related miRNAs

W Wang, L Liu, J Zhu, Y Xing, S Jiao, Z Wu - ACS nano, 2024 - ACS Publications
In biomedical testing, artificial intelligence (AI)-enhanced analysis has gradually been
applied to the diagnosis of certain diseases. This research employs AI algorithms to refine …

Based Analytical Devices for Cancer Liquid Biopsy

S Singh, A Raucci, W Cimmino, S Cinti - Analytical Chemistry, 2024 - ACS Publications
Liquid biopsies have caused a significant revolution in cancer diagnosis, and the use of
point of care (PoC) platforms has the potential to bring liquid biopsy-based cancer detection …

Electrochemical Biosensors for Cancer Diagnosis: Multitarget Analysis to Present Molecular Characteristics of Tumor Heterogeneity

Y Cao, J Xia, L Li, Y Zeng, J Zhao, G Li - JACS Au, 2024 - ACS Publications
Electrochemical biosensors are gaining attention as powerful tools in cancer diagnosis,
particularly in liquid biopsy, due to their high efficiency, rapid response, exceptional …

Simultaneous Detection of Micro-RNAs by a Disposable Biosensor via the Click Chemistry Connection Strategy

X Liu, Q Wang, J Li, Z Diao, J Hou, D Huo… - Analytical …, 2024 - ACS Publications
Simultaneous detection of multiple breast cancer-associated miRNAs significantly raises the
accuracy and reliability of early diagnosis. In this work, disposable carbon fiber paper serves …

based electrochemical device for early detection of integrin αvβ6 expressing tumors

S Cinti, S Tomassi, C Ciardiello, R Migliorino… - Communications …, 2024 - nature.com
Despite progress in the prevention and diagnosis of cancer, current technologies for tumor
detection present several limitations including invasiveness, toxicity, inaccuracy, lengthy …