Surfactant protein D in respiratory and non-respiratory diseases

GL Sorensen - Frontiers in medicine, 2018 - frontiersin.org
Surfactant protein D (SP-D) is a multimeric collectin that is involved in innate immune
defense and expressed in pulmonary, as well as non-pulmonary, epithelia. SP-D exerts …

The role of protein corona on nanodrugs for organ-targeting and its prospects of application

S Wang, J Zhang, H Zhou, YC Lu, X Jin, L Luo… - Journal of Controlled …, 2023 - Elsevier
Nowadays, nanodrugs become a hotspot in the high-end medical field. They have the ability
to deliver drugs to reach their destination more effectively due to their unique properties and …

Collectins and ficolins: humoral lectins of the innate immune defense

U Holmskov, S Thiel… - Annual review of …, 2003 - annualreviews.org
Collectins and ficolins, present in plasma and on mucosal surfaces, are humoral molecules
of the innate immune systems, which recognize pathogen-associated molecular patterns …

Surfactant proteins SP-A and SP-D: structure, function and receptors

U Kishore, TJ Greenhough, P Waters, AK Shrive… - Molecular …, 2006 - Elsevier
Surfactant proteins, SP-A and SP-D, are collagen-containing C-type (calcium dependent)
lectins called collectins, which contribute significantly to surfactant homeostasis and …

Surfactant proteins A and D and pulmonary host defense

E Crouch, JR Wright - Annual review of physiology, 2001 - annualreviews.org
▪ Abstract The lung collectins, SP-A and SP-D, are important components of the innate
immune response to microbial challenge and participate in other aspects of immune and …

Immunomodulatory functions of surfactant

JR Wright - Physiological reviews, 1997 - journals.physiology.org
The possibility that the lipoprotein complex of lung surfactant functions in pulmonary host
defense as well as lowering surface tension at the air-liquid interface has been the subject of …

Lipid–protein and protein–protein interactions in the pulmonary surfactant system and their role in lung homeostasis

O Cañadas, B Olmeda, A Alonso… - International journal of …, 2020 - mdpi.com
Pulmonary surfactant is a lipid/protein complex synthesized by the alveolar epithelium and
secreted into the airspaces, where it coats and protects the large respiratory air–liquid …

The pulmonary surfactant system: biochemical and clinical aspects

L Creuwels, LMG Van Golde, HP Haagsman - Lung, 1997 - Springer
This article starts with a brief account of the history of research on pulmonary surfactant. We
will then discuss the morphological aspects and composition of the pulmonary surfactant …

An insight into the diverse roles of surfactant proteins, SP-A and SP-D in innate and adaptive immunity

A Nayak, E Dodagatta-Marri, AG Tsolaki… - Frontiers in …, 2012 - frontiersin.org
Surfactant proteins SP-A and SP-D are hydrophilic, collagen-containing calcium-dependent
lectins, which appear to have a range of innate immune functions at pulmonary as well as …

Pulmonary surfactant: an immunological perspective

Z Chroneos, Z Sever-Chroneos… - Cellular Physiology and …, 2009 - karger.com
Pulmonary surfactant has two crucial roles in respiratory function; first, as a biophysical entity
it reduces surface tension at the air water interface, facilitating gas exchange and alveolar …