Implantable drug delivery systems and foreign body reaction: Traversing the current clinical landscape
A Fayzullin, A Bakulina, K Mikaelyan, A Shekhter… - Bioengineering, 2021 - mdpi.com
Precise delivery of therapeutics to the target structures is essential for treatment efficiency
and safety. Drug administration via conventional routes requires overcoming multiple …
and safety. Drug administration via conventional routes requires overcoming multiple …
[HTML][HTML] Pharmacological approaches for the prevention of breast implant capsular contracture
Capsular contracture is a common complication associated with breast implants following
reconstructive or aesthetic surgery in which a tight or constricting scar tissue capsule forms …
reconstructive or aesthetic surgery in which a tight or constricting scar tissue capsule forms …
[HTML][HTML] SMI-Capsular Fibrosis and Biofilm Dynamics: Molecular Mechanisms, Clinical Implications, and Antimicrobial Approaches
I Schoberleitner, M Lackner, DC Coraça-Huber… - International Journal of …, 2024 - mdpi.com
Silicone mammary implants (SMIs) frequently result in capsular fibrosis, which is marked by
the overproduction of fibrous tissue surrounding the implant. This review provides a detailed …
the overproduction of fibrous tissue surrounding the implant. This review provides a detailed …
Semipermeable barrier-assisted electrophoretic deposition of robust collagen membranes
A Antoshin, O Dubinin, L Miao, E Istranova… - Journal of Materials …, 2023 - Springer
Collagen membranes with high robustness and a defined stable biodegradation are of a
great interest for dental surgery. Electrophoretic deposition (EPD) is a perspective candidate …
great interest for dental surgery. Electrophoretic deposition (EPD) is a perspective candidate …
Biomaterials and extracellular vesicle delivery: current status, applications and challenges
In this review, we will discuss the current status of extracellular vesicle (EV) delivery via
biopolymeric scaffolds for therapeutic applications and the challenges associated with the …
biopolymeric scaffolds for therapeutic applications and the challenges associated with the …
Implants as targeted drug delivery systems
EO Bakhrushina, NB Demina - Pharmaceutical Chemistry Journal, 2022 - Springer
This review considers implants as modern drug delivery systems. Methods of their
production by hot melt extrusion, direct pressing, and 3D printing are described. The …
production by hot melt extrusion, direct pressing, and 3D printing are described. The …
An electrospun macrodevice for durable encapsulation of human cells with consistent secretion of therapeutic antibodies
S Imaichi-Kobayashi, R Kassab, A Piersigilli… - Biomaterials, 2023 - Elsevier
Frequent subcutaneous or intravenous administrations of therapeutic biomolecules can be
costly and inconvenient for patients. Implantation of encapsulated recombinant cells …
costly and inconvenient for patients. Implantation of encapsulated recombinant cells …
Passivated Hydrogel Interface: Armor Against Foreign Body Response and Inflammation in Small-Diameter Vascular Grafts
M Zhou, Z Wang, M Li, Q Chen, S Zhang, J Wang - Biomaterials, 2024 - Elsevier
The development of small-diameter vascular grafts (SDVG) still faces significant challenges,
particularly in overcoming blockages within vessels. A key issue is the foreign-body …
particularly in overcoming blockages within vessels. A key issue is the foreign-body …
Surface topography of PLA implants defines the outcome of foreign body reaction: An in vivo study
E Ivanova, A Fayzullin, N Minaev, I Dolganova… - Polymers, 2023 - mdpi.com
The formation of a dense fibrous capsule around the foreign body and its contracture is the
most common complication of biomaterial implantation. The aim of our research is to find out …
most common complication of biomaterial implantation. The aim of our research is to find out …
A defined road to tracheal reconstruction: laser structuring and cell support for rapid clinic translation
A Fayzullin, G Vladimirov, A Kuryanova… - Stem Cell Research & …, 2022 - Springer
One of the severe complications occurring because of the patient's intubation is tracheal
stenosis. Its incidence has significantly risen because of the COVID-19 pandemic and tends …
stenosis. Its incidence has significantly risen because of the COVID-19 pandemic and tends …