Co-expression of drug metabolizing cytochrome P450 enzymes and estrogen receptor alpha (ESR1) in human liver: racial differences and the regulatory role of ESR1

JM Collins, D Wang - Drug metabolism and personalized therapy, 2021 - degruyter.com
Objectives The function and expression of cytochrome P450 (CYP) drug metabolizing
enzymes is highly variable, greatly affecting drug exposure, and therapeutic outcomes. The …

Investigation of miR-26a-5p and miR-19a-3p expression levels in angiographically confirmed coronary artery disease

N Coban, AF Erkan, AS Ozuynuk-Ertugrul… - Acta …, 2023 - Taylor & Francis
Background MicroRNAs have been found to have an essential role in cardiovascular
diseases. In previous experiments, the changed expressions of miR-26a-5p and miR-19a …

Pathway analysis of sepsis-induced changes gene expression

AA Elbakkoush, A Khaleel, ANA Mohamed… - Egyptian Journal of …, 2022 - Springer
Background Sepsis reaction is a response to an infection composed of genetic elements.
This research aims to better understand how sepsis affects the molecular pathways in whole …

Association of the ESR1 (rs9340799), OLR1 (rs3736234), LIPC (rs2070895), VDR (rs2228570), and CETP (rs708272) Polymorphisms With Risk of Coronary …

ZM Karam, A Yari, A Najmadini… - Journal of Clinical …, 2024 - Wiley Online Library
Background Coronary artery disease (CAD) is a devastating illness and a leading cause of
death worldwide, primarily caused by atherosclerosis resulting from a genetic …

Uncovering the Protective Mechanism of the Volatile Oil of Acorus tatarinowii against Acute Myocardial Ischemia Injury Using Network Pharmacology and …

ZZ Zang, LM Chen, Y Liu, YM Guan… - Evidence‐Based …, 2021 - Wiley Online Library
Acorus tatarinowii is a traditional aromatic resuscitation drug that can be clinically used to
prevent cardiovascular diseases. The volatile oil of Acorus tatarinowii (VOA) possesses …

Correlation Between Estrogen Receptor α Gene Polymorphism (c454-397T> C) with Serum Estradiol Levels and Known Risk Factors in Patients with Myocardial …

RR Aparna, D Rajarajeswari, M Prasad… - Indian Journal of Clinical …, 2023 - Springer
Myocardial infarction (MI) remains the most common cause of cardiac failure and continuous
increasing rate of morbidity and mortality. We aimed to investigate the association of …

Identification of novel key genes and signaling pathways in hypertrophic cardiomyopathy: evidence from bioinformatics and next generation sequencing data analysis

BM Vastrad, CM Vastrad - bioRxiv, 2024 - biorxiv.org
Hypertrophic cardiomyopathy (HCM) is a global health problem characterized by left
ventricle become thick and stiff with effect of indication including chest pain, fluttering …

Genetic Polymorphisms and Risk of Cardiovascular Disease

SM Okda, AB Kassem, A Salahuddin… - … Journal of Clinical …, 2023 - pharaohacademy.com
Cardiovascular disease (CVD) is the major cause of death and disability worldwide. Major
and well-established cardiovascular disease risk factors include advancing age, male sex …

Морфогенетичні особливості гіперпластичних процесів ендометрія

НЛ Циндренко - 2024 - essuir.sumdu.edu.ua
Актуальність дослідження гіперпластичних процесів ендометрія (ГПЕ) обумовлена
значною поширеністю цієї патології у жінок різного віку, високим потенціалом до …

[PDF][PDF] Epigenetic of the Estrogen Receptors in Women Healthy Aging

E Gardini - 2020 - zora.uzh.ch
Life expectancy is currently increasing more rapidly than healthy life expectancy, especially
for women. Menopause is a unique biological process in women that is concurrent with …