Natural products play a significant role in human health in relation to the prevention and
treatment of inflammatory conditions. Among them, terpenoids (also referred to as terpenes) …

Acne vulgaris is the most common skin condition associated with inflammation of
pilosebaceous unit. Since conventional therapies have not demonstrated desirable …

A palladium-catalyzed cascade carbonylative spirolactonization of hydroxycyclopropanols
has been developed to efficiently synthesize oxaspirolactones common to many complex …

Abstract Ethopharmacological relevance Mitragyna speciosa Korth (Rubiaceae) is one of
the medicinal plants used traditionally to treat various types of diseases especially in …

The search for new anti-inflammatory agents is challenging due to the complexity of the
inflammatory process and its role in host defense. Over the past few decades, a significant …

Inflammation is a complex biological response that in spite of having available treatments,
their side effects limit their usefulness. Because of this, natural products have been the …

Copaifera spp. are Amazonian species widely studied and whose oleoresins are used by
local people for various medicinal purposes. However, a detailed study of the activity of the …

Spirobutenolides and spirobutyrolactones structural motifs are widespread in various natural
products that exhibit a broad array of biological activities. Additionally, their synthetic …

Background Plants from the genus Ocimum are used as folk medicine for treating various
diseases including inflammatory and immune-related diseases. Numerous reports have …

Macrophages are highly plastic cells that adopt different functional phenotypes in response
to environmental signals. Classically activated macrophages (M1) exhibit a pro-inflammatory …