Protein aggregation leading to the formation of amyloid fibrils has various adverse effects on
human health ranging from fatigue and numbness to organ failure and death in extreme …

Insulin is a therapeutically relevant molecule with use in treating diabetes patients.
Unfortunately, it undergoes a range of untoward and often unpredictable physical …

Objective: The purpose of this study was to evaluate the effects of the antimicrobial
photodynamic therapy (a-PDT) with blue light and curcumin on oral disinfection during the 2 …

Type-2 diabetes mellitus (T2DM) is one of the most concerning public health problems
because of its high incidence, multiple complications, and difficult treatment. Human islet …

El objetivo de la presente investigación fue analizar empíricamente la relación entre
innovación, emprendimiento y desarrollo local del pueblo de Salinas de Guaranda …

Exogenous insulin, used as a therapeutic agent for diabetes, forms insoluble deposits
containing amyloid fibrillar structures near the administration site. We have analyzed the in …

Protein misfolding and related formation of amyloid fibrils are associated with several
conformational diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD) …

Curcumin is known for its anti-inflammatory, antioxidant and anticancer activity, as well as for
its ability to interfere with amyloid aggregation and non-enzymatic glycation reaction, that …

We report here the inhibition of amyloid fibrillation of human insulin in vitro by Morin hydrate,
a naturally occurring small molecule. Using spectroscopic assays and transmission electron …

The self-assembly of insulin to form amyloid fibrils has been widely studied because it is a
significant problem in the medical management of diabetes and is an important model …