Voltage-gated calcium channels are required for many key functions in the body. In this
review, the different subtypes of voltage-gated calcium channels are described and their …

Voltage-gated calcium channels are the primary mediators of depolarization-induced
calcium entry into neurons. There is great diversity of calcium channel subtypes due to …

The function of a cell is defined by its intrinsic characteristics and its niche: the tissue
microenvironment in which it dwells. Here we combine single-cell and spatial …

Voltage‐gated calcium channels are essential players in many physiological processes in
excitable cells. There are three main subdivisions of calcium channel, defined by the pore …

Voltage-gated calcium channels are important regulators of brain, heart and muscle
functions, and their dysfunction can give rise to pathophysiological conditions ranging from …

Adrenal aldosterone-producing adenomas (APAs) constitutively produce the salt-retaining
hormone aldosterone and are a common cause of severe hypertension. Recurrent …

Sensorineural hearing impairment is the most common form of hearing loss, and
encompasses pathologies of the cochlea and the auditory nerve. Hearing impairment …

At least 5% of individuals with hypertension have adrenal aldosterone-producing adenomas
(APAs). Gain-of-function mutations in KCNJ5 and apparent loss-of-function mutations in …

The domestication of the horse∼ 5.5 kya and the emergence of mounted riding, chariotry,
and cavalry dramatically transformed human civilization. However, the genetics underlying …

This review summarises genetic studies in which calcium channel genes have been
connected to the spectrum of neuropsychiatric syndromes, from bipolar disorder and …