The blood–brain barrier (BBB) plays a vital role in maintaining the specialized
microenvironment of the neural tissue. It separates the peripheral circulatory system from the …

Stroke is the second most common cause of death and the leading cause of disability
worldwide. Brain injury following stroke results from a complex series of pathophysiological …

Vascular cognitive impairment and dementia (VCID) is a major heterogeneous brain
disease caused by multiple factors, and it is the second most common type of dementia in …

Vascular dementia (VaD) is the second leading form of dementia after Alzheimer's disease
(AD) plaguing the elderly population. VaD is a progressive disease caused by reduced …

Remote ischaemic conditioning (RIC) triggers endogenous protective pathways in distant
organs such as the kidney, heart and brain, and represents an exciting new paradigm in …

While prevailing evidence supports that the amyloid cascade hypothesis is a key component
of Alzheimer's disease (AD) pathology, many recent studies indicate that the vascular …

Vascular dementia (VD) is defined as a progressive neurodegenerative disease of cognitive
decline, attributable to cerebrovascular factors. Numerous studies have demonstrated that …

Background and Purpose—We aimed to evaluate the efficacy of remote ischemic
conditioning (RIC) in patients with cerebral small-vessel disease. Methods—Thirty patients …

Inflammation is an important mediator of secondary neurological injury after traumatic brain
injury (TBI). Endocannabinoids, endogenously produced arachidonate based lipids, have …

Metabolic aberrations impact the pathogenesis of multiple sclerosis (MS) and possibly can
provide clues for new treatment strategies. Using untargeted metabolomics, we measured …