New therapies for human cytomegalovirus infections

WJ Britt, MN Prichard - Antiviral research, 2018 - Elsevier
The recent approval of letermovir marks a new era of therapy for human cytomegalovirus
(HCMV) infections, particularly for the prevention of HCMV disease in hematopoietic stem …

Epstein-Barr virus and cytomegalovirus infections of the liver

C Bunchorntavakul, KR Reddy - Gastroenterology Clinics, 2020 - gastro.theclinics.com
Epstein-Barr virus (EBV) and cytomegalovirus (CMV) are human herpesviruses (HHV) that
are common in humans. Primary EBV and CMV infections mostly are asymptomatic but can …

Practical recommendations for long-term management of modifiable risks in kidney and liver transplant recipients: a guidance report and clinical checklist by the …

JM Neuberger, WO Bechstein, DRJ Kuypers… - …, 2017 - journals.lww.com
Short-term patient and graft outcomes continue to improve after kidney and liver
transplantation, with 1-year survival rates over 80%; however, improving longer-term …

Acute allograft rejection in liver transplant recipients: Incidence, risk factors, treatment success, and impact on graft failure

N Dogan, A Hüsing-Kabar… - Journal of …, 2018 - journals.sagepub.com
Objective This study was performed to identify risk factors for acute cellular rejection after
liver transplantation (LT). Methods Consecutive LT recipients who underwent surgery in our …

Single-cycle adenovirus vectors in the current vaccine landscape

M Barry - Expert review of vaccines, 2018 - Taylor & Francis
Introduction: Traditional inactivated and protein vaccines generate strong antibodies, but
struggle to generate T cell responses. Attenuated pathogen vaccines generate both, but risk …

Distribution and effects of amino acid changes in drug-resistant α and β herpesviruses DNA polymerase

D Topalis, S Gillemot, R Snoeck… - Nucleic acids …, 2016 - academic.oup.com
Emergence of drug-resistance to all FDA-approved antiherpesvirus agents is an increasing
concern in immunocompromised patients. Herpesvirus DNA polymerase (DNApol) is …

In vitro evaluation of current and novel antivirals in combination against human cytomegalovirus

MS O'Brien, KC Markovich, D Selleseth, AV DeVita… - Antiviral research, 2018 - Elsevier
Human cytomegalovirus (HCMV) can cause severe disease in patients with compromised or
immature immune systems. Currently approved pharmacotherapies for the treatment of …

[HTML][HTML] Cytomegalovirus infection in liver-transplanted children

N Onpoaree, A Sanpavat, P Sintusek - World Journal of Hepatology, 2022 - ncbi.nlm.nih.gov
Cytomegalovirus (CMV) infection is a common complication of liver trans-plantation in
children. The CMV serostatus of recipients and donors is the primary risk factor, and …

Incidence, predictors, and impact on survival of long-term cardiovascular events after liver transplantation

L Sastre, R Garcia, JG Gandara, P Ruiz… - …, 2020 - journals.lww.com
Background: Information on the risk factors, particularly kidney function, and impact of long-
term cardiovascular events (CVE) after liver transplantation (LT) remains scarce. Methods …

A narrative review of the evaluation and management of liver transplant complications in the emergency department

R El Sibai, SR Freedman, JD Gatz - The Journal of emergency medicine, 2023 - Elsevier
Background Liver transplant recipients are prone to both short-term and long-term
complications and may present to any emergency department. Objective This narrative …