Mastocytosis is a hematologic neoplasm characterized by expansion and focal
accumulation of neoplastic mast cells (MC) in diverse organs, including the skin, bone …

Over the past few years, substantial advances have been made in understanding the
pathogenesis, evolution, and complexity of mast cell neoplasms. New diagnostic and …

Cutaneous lesions in patients with mastocytosis are highly heterogeneous and encompass
localized and disseminated forms. Although a classification and criteria for cutaneous …

Mastocytosis is a heterogeneous group of neoplasms defined by a numerical increase and
accumulation of clonal mast cells (MCs) in various organ systems. The disease may present …

Mastocytosis is a term used to denote a heterogeneous group of conditions defined by the
expansion and accumulation of clonal (neoplastic) tissue mast cells in various organs. The …

Activation of tissue mast cells (MCs) and their abnormal growth and accumulation in various
organs are typically found in primary MC disorders also referred to as mastocytosis …

Clinical phenotype in systemic mastocytosis (SM) is markedly variable, which complicates
prognostication and decision making regarding the choice and timing of therapy. In a …

Although a classification for mastocytosis and diagnostic criteria are available, there remains
a need to define standards for the application of diagnostic tests, clinical evaluations, and …

Methods This article is based on a selective literature search and on the authors' clinical and
pathological experience. Results The clinical manifestations of mastocytosis range from …

Mast cells have been recognized for well over 100 years. With time, human mast cells have
been documented to originate from CD34+ cells, and have been implicated in host …